Development of Visual Field Screening Procedures: A Case Study of the Octopus Perimeter

被引:13
作者
Turpin, Andrew [1 ]
Myers, Jonathan S. [2 ]
McKendrick, Allison M. [3 ]
机构
[1] Univ Melbourne, Dept Comp & Informat Syst, Melbourne, Vic 3010, Australia
[2] Wills Eye Hosp & Res Inst, Philadelphia, PA USA
[3] Univ Melbourne, Dept Optometry & Vis Sci, Melbourne, Vic, Australia
关键词
visual field; screening; glaucoma; FREQUENCY-DOUBLING TECHNOLOGY; AUTOMATED PERIMETRY; GLAUCOMA; VARIABILITY; SUPRATHRESHOLD; PATTERN; PERFORMANCE; LOCATIONS; DEFECTS; POINTS;
D O I
10.1167/tvst.5.3.3
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Purpose: We develop a methodology for designing perimetric screening procedures, using Octopus perimeters as a case study. Methods: The process has three stages: analytically determining specificity and number of presentations required for different multisampling suprathreshold schemes at a single location of the visual field, ranking visual field locations by their positive predictive value (PPV) for glaucoma, and determining a pass/fail criteria for the test. For the case study the Octopus G-program visual field test pattern is used, and a dataset of 385 glaucoma and 86 normal patients. Results: Using a 1-of-3 sampling strategy at a level equal to the 95 percentile of normal observers gave the most robust specificity under the influences of false-negative responses using an average of 1.5 presentations per location. The PPV analysis gave 19 locations that completely classified our glaucomatous data. A further 9 points were added to screen for nonglaucomatous loss. The final stage found that insisting that 3 locations are missed for the screening to fail gave a simulated specificity and sensitivity of approximately 95% for unreliable responders. Conclusions: Our method gives a principled approach to choosing between the many parameters of a visual field screening procedure. We have developed a procedure for the Octopus that should terminate in less than 1 minute for normal observers with high specificity and sensitivity to glaucoma.
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页数:9
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