Ultra highspeed in-vivo Fourier domain full-field OCT of the human retina

被引：1

作者：

Bonin, Tim ^{[1
]}

Hagen-Eggert, Martin ^{[2
]}

Franke, Gesa ^{[1
]}

Koch, Peter ^{[3
]}

Huettmann, Gereon ^{[1
,2
]}

机构：

[1] Univ Lubeck, Inst Biomed Opt, Peter Monnik Weg 4, D-23562 Lubeck, Germany

[2] Med Laser Ctr Lubeck GmbH, D-23562 Lubeck, Germany

[3] Thorlabs GmbH, D-23562 Lubeck, Germany

来源：

OPTICAL COHERENCE TOMOGRAPHY AND COHERENCE DOMAIN OPTICAL METHODS IN BIOMEDICINE XV | 2011年 / 7889卷

关键词：

Optical coherence tomography; Lasers (tunable); Three-dimensional image acquisition; Ultrafast measurements; OPTICAL COHERENCE TOMOGRAPHY;

D O I：

10.1117/12.874970

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

In-vivo full field (FF) optical coherence tomography (OCT) images of human retina with up to 6.8 million A-lines/s are presented by using a rapidly tunable laser source in combination with an ultra-high speed CMOS camera. It is shown that Fourier domain (FD) full field OCT could provide a way to overcome limitations in imaging speed which are posed by the maximal possible exposure (MPE) of the retina. With a 100 Hz sweep rate FF-OCT was fast enough to acquire OCT images without motion artifacts, but with rather low sensitivity of 77 dB limited by an undesired incoherent background. Nevertheless, FF-OCT may become an attractive alternative for ultrafast retinal imaging boosting image speed by a lack of moving parts and the use of considerably higher irradiation power, if it is possible to to increase the sensitivity by reducing incoherent straylight.

引用

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