In vivo bone strain and finite element modeling of a rhesus macaque mandible during mastication

被引:23
作者
Panagiotopoulou, Olga [1 ,2 ]
Iriarte-Diaz, Jose [3 ]
Wilshin, Simon [4 ]
Dechow, Paul C. [5 ]
Taylor, Andrea B. [6 ]
Abraha, Hyab Mehari [1 ]
Aljunid, Sharifah F. [7 ]
Ross, Callum F. [8 ]
机构
[1] Univ Queensland, Sch Biomed Sci, Moving Morphol & Funct Mech Lab, Brisbane, Qld 4072, Australia
[2] Monash Univ, Fac Med Nursing & Hlth Sci, Sch Biomed Sci, Dept Anat & Dev Biol, Melbourne, Vic 3800, Australia
[3] Univ Illinois, Dept Oral Biol, 801 S Paulina St, Chicago, IL 60612 USA
[4] Royal Vet Coll, Dept Biomed Sci, Hawkshead Lane, Hatfield AL9 7TA, Herts, England
[5] Texas A&M Univ, Coll Dent, Dept Biomed Sci, 3302 Gaston Ave, Dallas, TX 75246 USA
[6] Touro Univ, Dept Basic Sci, 1310 Club Dr, Vellejo, CA 94592 USA
[7] Menara OBYU, Mat Unit 5 01, 4,Jalan PJU 8-8A, Petaling Jaya 47820, Selangor, Malaysia
[8] Univ Chicago, Dept Organismal Biol & Anat, 1027 E 57th St, Chicago, IL 60637 USA
基金
美国国家卫生研究院; 美国国家科学基金会;
关键词
Finite element analysis; Bone strain gauges; Chewing; Musculoskeletal modeling; Bone material properties;
D O I
10.1016/j.zool.2017.08.010
中图分类号
Q95 [动物学];
学科分类号
071002 ;
摘要
Finite element analysis (FEA) is a commonly used tool in musculoskeletal biomechanics and vertebrate paleontology. The accuracy and precision of finite element models (FEMs) are reliant on accurate data on bone geometry, muscle forces, boundary conditions and tissue material properties. Simplified modeling assumptions, due to lack of in vivo experimental data on material properties and muscle activation patterns, may introduce analytical errors in analyses where quantitative accuracy is critical for obtaining rigorous results. A subject specific FEM of a rhesus macaque mandible was constructed, loaded and validated using in vivo data from the same animal. In developing the model, we assessed the impact on model behavior of variation in (i) material properties of the mandibular trabecular bone tissue and teeth; (ii) constraints at the temporomandibular joint and bite point; and (iii) the timing of the muscle activity used to estimate the external forces acting on the model. The best match between the FEA simulation and the in vivo experimental data resulted from modeling the trabecular tissue with an isotropic and homogeneous Young's modulus and Poisson's value of 10 GPa and 0.3, respectively; constraining translations along X,Y, Z axes in the chewing (left) side temporomandibular joint, the premolars and the m(1); constraining the balancing (right) side temporomandibular joint in the anterior-posterior and superior-inferior axes, and using the muscle force estimated at time of maximum strain magnitude in the lower lateral gauge. The relative strain magnitudes in this model were similar to those recorded in vivo for all strain locations. More detailed analyses of mandibular strain patterns during the power stroke at different times in the chewing cycle are needed.
引用
收藏
页码:13 / 29
页数:17
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