Adrenocortical carcinoma - Many questions remain unanswered

被引:1
作者
Geller, JL
Mertens, RB
Weiss, LM
机构
[1] Cedars Sinai Med Ctr, Div Endocrinol Diabet & Metab, Dept Internal Med, Los Angeles, CA 90048 USA
[2] Cedars Sinai Med Ctr, Dept Pathol & Lab Med, Los Angeles, CA 90048 USA
[3] City Hope Natl Med Ctr, Div Pathol, Duarte, CA 91010 USA
关键词
adrenal carcinoma; adrenocortical carcinoma; adrenal malignancy; Cushing syndrome; endocrine neoplasms;
D O I
10.1097/01.ten.0000179019.26435.ad
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Adrenocortical carcinoma is a rare and aggressive malignancy with varying presentations. Histologic criteria for distinguishing malignancy from benignity are challenging and make it difficult to assign a clear prognosis. Furthermore, there remain many uncertainties regarding optimal medical and surgical treatments. In this review, we describe the epidemiology, clinical presentation, pathogenesis, pathology, and treatment of adrenocortical carcinoma with specific attention to areas of uncertainty and controversy.
引用
收藏
页码:309 / 312
页数:4
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