Ultrasound-promoted an efficient method for the one-pot synthesis of indeno fused pyrido[2,3-d] pyrimidines catalyzed by H3PW12O40 functionalized chitosan@Co3O4 as a novel and green catalyst

A novel magnetically recoverable nanocomposite including Co3O4/chitosan/H3PW12O40 (Co3O4/CS/PWA) as a heterogeneous catalyst was prepared using a facile synthetic method and characterized by FT-IR, XRD, SEM, VSM and EDX. A simple, efficient and rapid synthesis of indeno[2',1':5,6] pyrido[2,3-d] pyrimidines was accomplished in excellent yields via one-pot three-component reaction of 1,3-dimethyl-6-aminouracil, aryl aldehydes and 1,3-indandione in the presence of amount of Co3O4/CS/PWA catalyst under ultrasound irradiation. Then, the catalyst was recovered with an external magnet and reused several times without significant loss of reactivity. (C) 2018 Published by Elsevier B.V.