Utility loss and indirect costs following cardiovascular events in hypertensive patients:: the ASCOT health economic substudy

被引：24

作者：

Lindgren, Peter ^{[2
]}

Kahan, Thomas ^{[1
]}

Poulter, Neil ^{[3
]}

Buxton, Martin ^{[4
]}

Svarvar, Patrick ^{[5
]}

Dahlof, Bjorn ^{[6
]}

Jonsson, Bengt ^{[7
]}

机构：

[1] Danderyd Hosp, Karolinska Inst, Stockholm, Sweden

[2] European Hlth Econ, S-11120 Stockholm, Sweden

[3] Univ London Imperial Coll Sci Technol & Med, London, England

[4] Brunel Univ, Uxbridge UB8 3PH, Middx, England

[5] Pfizer Inc, New York, NY USA

[6] Sahlgrens Univ Hosp, S-41345 Gothenburg, Sweden

[7] Stockholm Sch Econ, Ctr Hlth Econ, S-11383 Stockholm, Sweden

来源：

EUROPEAN JOURNAL OF HEALTH ECONOMICS | 2007年 / 8卷 / 01期

关键词：

cardiovascular disease; costs; quality of life; Sweden;

D O I：

10.1007/s10198-006-0002-9

中图分类号：

F [经济];

学科分类号：

02 ;

摘要：

This study assessed the loss of utility and indirect costs associated with first cardiovascular events. Data was collected (using EQ-5D) prospectively at 3, 6, and 12 months following an event in the Swedish part of the Anglo-Scandinavian cardiac outcomes trial (ASCOT), including patients with mild to moderate hypertension and additional risk factors. Sixty patients were eligible for analysis. An event was associated with a one-year utility loss of 0.075 (95% CI: 0.038-0.114). For a stroke, the reduction was 0.1.45 (CI: 0.059-0.249) and for acute coronary syndromes (myocardial infarction or unstable angina) the loss was 0.051 (-0.003 to 0.103). The utility at baseline was no different to the utility in a control group. The indirect cost over the first 12 months (2003 Swedish Kronor, SEK) was 90028 SEK (CI: 46027-146754), 9866 E for patients in the workforce. These results are helpful in future economic evaluations of primary preventive measures in cardiovascular medicine.

引用

页码：25 / 30

页数：6

共 20 条

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