Functional and Survival Outcomes of Patients following the Harrington Procedure for Complex Acetabular Metastatic Lesions

被引:5
作者
Plaud, Andrea [1 ]
Gaillard, Jean [1 ]
Gouin, Francois [2 ]
Le Thuaut, Aurelie [3 ]
Ageneau, Peggy [1 ]
Berchoud, Juliane [1 ]
Fouasson-Chailloux, Alban [4 ,5 ]
Crenn, Vincent [1 ,6 ]
机构
[1] Nantes Univ, CHU Nantes, Clin Chirurg Orthoped & Traumatol, 1 Pl Alexis Ricordeau, F-44000 Nantes, France
[2] Ctr Lutte Canc Leon Berard, Dept Chirurg, F-69008 Lyon, France
[3] Nantes Univ, CHU Nantes, Direct Rech & Innovat, Plateforme Methodol & Biostat, F-44000 Nantes, France
[4] Nantes Univ, CHU Nantes, Med Phys & Readaptat Locomotrice, 85 Rue St Jacques, F-44093 Nantes, France
[5] Nantes Univ, ONIRIS, RMeS, Regenerat Med & Skeleton,INSERM UMR 1229, F-44042 Nantes, France
[6] Nantes Univ, CRCI2NA Ctr Rech Cancerol & Immunol Nantes Angers, CNRS UMR 6075, INSERM UMR 1307,Team CHILD CHromatin & Transcript, 1 Rue Gaston Veil, F-44035 Nantes, France
关键词
acetabular lesion; bone metastasis; Harrington procedure; functional assessment; TOTAL HIP-ARTHROPLASTY; PROGNOSTIC-FACTORS; SURGICAL-TREATMENT; SCORING SYSTEM; RECONSTRUCTION; MANAGEMENT; DISEASE;
D O I
10.3390/curroncol29080464
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Background: The Harrington surgical technique makes it possible to manage complex, extensive bone lesions using pins and cement to consolidate bone for acetabular cup positioning. However, it may be associated with a high reoperation rate, and the functional results of this surgery are not precisely described in the literature. Methods: In a monocentric retrospective study including all patients operated on using the Harrington procedure associated with THA between 2005 and 2020, we aimed to assess preoperative and postoperative function, reoperation-free survival, and overall survival. Results: Functional improvement was significant for Parker scores (preoperative: 3.6 +/- 2.0; 6-month follow-up: 6.6 +/- 3.2; 12-month follow-up: 7.6 +/- 2.1) and Musculoskeletal Tumor Society (MSTS) scores (preoperative: 31.1 +/- 16.2%; 6-month follow-up: 67.7 +/- 30.6%; 12-month follow-up: 82.4 +/- 24.0%). Of the 21 patients included, the reoperation-free survival rate was 76.1% [CI 95%: 58.1-99.7] at six and twelve months, with the main complications being pin migration (50.0%) and infection (25%). The patient overall survival rate was 76.2% [95% CI: 59.9-96.7] at six months and 61.9% [95% CI: 59.9-96.7] at 12 months. Discussion: These results underlined significant functional improvements following a conventional Harrington procedure, with acceptable reoperation rates.
引用
收藏
页码:5875 / 5890
页数:16
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