Enantioselective reduction of ketones catalyzed by polymer-supported sulfonamide using NaBH4/Me3SiCl (or BF3•OEt2) as reducing agent

被引：0
|
作者：
Hu, JB [1 ]
Zhao, G [1 ]
Ding, ZD [1 ]
机构：
[1] Chinese Acad Sci, Shanghai Inst Organ Chem, Shanghai 200032, Peoples R China
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2001年 / 40卷 / 06期
关键词：
asymmetric synthesis; heterogeneous catalysis; reductions; sulfonamides;
D O I：
10.1002/1521-3773(20010316)40:6<1109::AID-ANIE11090>3.0.CO;2-T
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Two remarkable reducing agents NaBH4/Me3SiCl (or BF33·OEt2) in combination with a new kind of chiral, polymer-supported N-sulfonamide catalyst 1 were applied to the reduction of prochiral ketones giving excellent chemical yields and enantiomeric excesses [Eq. (1)].
引用
收藏
页码：1109 / +
页数：4
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