Genotype variation of Trypanosoma cruzi isolates from different Brazilian biomes

被引:19
作者
Araujo, C. A. C. [1 ]
Waniek, P. J. [1 ]
Xavier, S. C. C. [1 ]
Jansen, A. M. [1 ]
机构
[1] Fiocruz MS, Inst Oswaldo Cruz, Lab Biol Tripanosomatideos, BR-21045900 Rio De Janeiro, Brazil
关键词
Trypanosoma cruzi; Triatomines; Mammals; TcI-TcIIa-e (TcI-TcVI) DTUs; Chagas disease; CONGENITAL CHAGAS-DISEASE; TRIATOMA-BRASILIENSIS; RIBOSOMAL-RNA; MINI-EXON; LINEAGES; VECTOR; AREA; TCI; IDENTIFICATION; TRANSMISSION;
D O I
10.1016/j.exppara.2010.07.013
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
Chagas disease is an enzootic disease, in which the flagellate Trypanosoma cruzi infects a large variety of animals. Humans are accidentally infected due to the migration into wild environments. To identify T. cruzi discrete typing units (DTUs), 19 Brazilian isolates from different biomes and hosts were analyzed by PCR amplification of 24S alpha rRNA, 18S rRNA and mini-exon gene sequences. The majority of the isolates was classified as TcIIb (TcII) but subtypes TcIIc (TcIII) and TcIId (TcV) were also identified. In addition, in monkeys TcI was detected. (C) 2010 Elsevier Inc. All rights reserved.
引用
收藏
页码:308 / 312
页数:5
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