Diagnosis and management of invasive candidiasis in the ICU: an updated approach to an old enemy

被引：84

作者：

Calandra, Thierry ^{[1
]}

Roberts, Jason A. ^{[2
]}

Antonelli, Massimo ^{[3
]}

Bassetti, Matteo ^{[4
]}

Vincent, Jean-Louis ^{[5
]}

机构：

[1] Univ Lausanne, CHU Vaudois, Infect Dis Serv, Rue Bugnon 46, CH-1011 Lausanne, Switzerland

[2] Univ Queensland, Royal Brisbane & Womens Hosp, Burns Trauma & Crit Care Res Ctr, Butterfield St, Brisbane, Qld 4029, Australia

[3] Univ Cattolica Sacro Cuore, A Gemelli Univ Hosp, Dept Anesthesiol & Intens Care Med, Largo A Gemelli 8, I-00168 Rome, Italy

[4] Santa Maria Misericordia Univ Hosp, Div Infect Dis, Piazzale Santa MAria della Misericordia 15, I-33100 Udine, Italy

[5] Univ Libre Bruxelles, Erasme Hosp, Dept Intens Care, Route Lennik 808, B-1070 Brussels, Belgium

来源：

CRITICAL CARE | 2016年 / 20卷

基金：

英国医学研究理事会;

关键词：

INTENSIVE-CARE-UNIT; CRITICALLY-ILL PATIENTS; SYSTEMIC ANTIFUNGAL THERAPY; 3RD EUROPEAN CONFERENCE; FUNGAL-INFECTIONS; POSACONAZOLE EXPOSURE; BRITISH SOCIETY; CANDIDEMIA; EPIDEMIOLOGY; BLOOD;

D O I：

10.1186/s13054-016-1313-6

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Invasive fungal infections, particularly those caused by Candida species, are not uncommon in critically ill patients and are associated with considerable morbidity and mortality. Diagnosis and management of these infections can be challenging. In this review, we will briefly discuss recent epidemiological data on invasive candidiasis and current diagnostic approaches before concentrating on antifungal treatments.

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页数：6

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共 60 条

[1] Update on antifungal resistance in Aspergillus and Candida [J].

Arendrup, M. C. .

CLINICAL MICROBIOLOGY AND INFECTION, 2014, 20 :42-48

[2] Therapeutic drug monitoring (TDM) of antifungal agents: guidelines from the British Society for Medical Mycology [J].

Ashbee, H. Ruth ;

Barnes, Rosemary A. ;

Johnson, Elizabeth M. ;

Richardson, Malcolm D. ;

Gorton, Rebecca ;

Hope, William W. .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2014, 69 (05) :1162-1176

[3] PCR Diagnosis of Invasive Candidiasis: Systematic Review and Meta-Analysis [J].

Avni, Tomer ;

Leibovici, Leonard ;

Paul, Mical .

JOURNAL OF CLINICAL MICROBIOLOGY, 2011, 49 (02) :665-670

[4] Are prophylactic antifungals in highly colonized patients safe and effective? [J].

Bassetti, Matteo ;

Leon, Cristobal ;

Timsit, Jean Francois .

INTENSIVE CARE MEDICINE, 2015, 41 (07) :1336-1339

[5] Epidemiology, Species Distribution, Antifungal Susceptibility, and Outcome of Candidemia across Five Sites in Italy and Spain [J].

Bassetti, Matteo ;

Merelli, Maria ;

Righi, Elda ;

Diaz-Martin, Ana ;

Maria Rosello, Eva ;

Luzzati, Roberto ;

Parra, Anna ;

Trecarichi, Enrico Maria ;

Sanguinetti, Maurizio ;

Posteraro, Brunella ;

Garnacho-Montero, Jose ;

Sartor, Assunta ;

Rello, Jordi ;

Tumbarello, Mario .

JOURNAL OF CLINICAL MICROBIOLOGY, 2013, 51 (12) :4167-4172

[6] A research agenda on the management of intra-abdominal candidiasis: results from a consensus of multinational experts [J].

Bassetti, Matteo ;

Marchetti, Monia ;

Chakrabarti, Arunaloke ;

Colizza, Sergio ;

Garnacho-Montero, Jose ;

Kett, Daniel H. ;

Munoz, Patricia ;

Cristini, Francesco ;

Andoniadou, Anastasia ;

Viale, Pierluigi ;

Della Rocca, Giorgio ;

Roilides, Emmanuel ;

Sganga, Gabriele ;

Walsh, Thomas J. ;

Tascini, Carlo ;

Tumbarello, Mario ;

Menichetti, Francesco ;

Righi, Elda ;

Eckmann, Christian ;

Viscoli, Claudio ;

Shorr, Andrew F. ;

Leroy, Olivier ;

Petrikos, George ;

De Rosa, Francesco Giuseppe .

INTENSIVE CARE MEDICINE, 2013, 39 (12) :2092-2106

[7] The economic impact of rapid Candida species identification by T2Candida among high-risk patients [J].

Bilir, Sara Pinar ;

Ferrufino, Cheryl P. ;

Pfaller, Michael A. ;

Munakata, Julie .

FUTURE MICROBIOLOGY, 2015, 10 (07) :1133-1144

[8] Differential association of fluconazole dose and dose/MIC ratio with mortality in patients with Candida albicans and non-albicans bloodstream infection [J].

Brosh-Nissimov, T. ;

Ben-Ami, R. .

CLINICAL MICROBIOLOGY AND INFECTION, 2015, 21 (11) :1011-1017

[9] Outcomes of mechanically ventilated hematology patients with invasive pulmonary aspergillosis [J].

Burghi, Gaston ;

Lemiale, Virginie ;

Seguin, Amelie ;

Lambert, Jerome ;

Lacroix, Claire ;

Canet, Emmanuel ;

Moreau, Anne-Sophie ;

Ribaud, Patricia ;

Schnell, David ;

Mariotte, Eric ;

Schlemmer, Benoit ;

Azoulay, Elie .

INTENSIVE CARE MEDICINE, 2011, 37 (10) :1605-1612

[10] Incidence, characteristics and outcome of ICU-acquired candidemia in India [J].

Chakrabarti, Arunaloke ;

Sood, Prashant ;

Rudramurthy, Shivaprakash M. ;

Chen, Sharon ;

Kaur, Harsimran ;

Capoor, Malini ;

Chhina, Deepinder ;

Rao, Ratna ;

Eshwara, Vandana Kalwaje ;

Xess, Immaculata ;

Kindo, Anupama J. ;

Umabala, P. ;

Savio, Jayanthi ;

Patel, Atul ;

Ray, Ujjwayini ;

Mohan, Sangeetha ;

Iyer, Ranganathan ;

Chander, Jagdish ;

Arora, Anita ;

Sardana, Raman ;

Roy, Indranil ;

Appalaraju, B. ;

Sharma, Ajanta ;

Shetty, Anjali ;

Khanna, Neelam ;

Marak, Rungmei ;

Biswas, Sanjay ;

Das, Shukla ;

Harish, B. N. ;

Joshi, Sangeeta ;

Mendiratta, Deepak .

INTENSIVE CARE MEDICINE, 2015, 41 (02) :285-295

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