Magnetic Nanoparticles for Antibiotics Detection

被引:53
作者
Cristea, Cecilia [1 ]
Tertis, Mihaela [1 ]
Galatus, Ramona [2 ]
机构
[1] Iuliu Hatieganu Univ Med & Pharm, Analyt Chem Dept, Fac Pharm, 4 Pasteur St, Cluj Napoca 400349, Romania
[2] Tech Univ Cluj Napoca, Basis Elect Dept, Fac Elect Telecommun & Informat Technol, 28 Memorandumului St, Cluj Napoca 400114, Romania
关键词
antibiotics; magnetic nanoparticles; electrochemical and optical sensors; detection; SURFACE-PLASMON RESONANCE; SUPERPARAMAGNETIC IRON-OXIDE; WALLED CARBON NANOTUBES; LABEL-FREE DETECTION; PERFORMANCE LIQUID-CHROMATOGRAPHY; MOLECULARLY IMPRINTED POLYMERS; CORE-SHELL NANOPARTICLES; BETA-LACTAM ANTIBIOTICS; SOLID-PHASE EXTRACTION; SULFONAMIDE ANTIBIOTICS;
D O I
10.3390/nano7060119
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Widespread use of antibiotics has led to pollution of waterways, potentially creating resistance among freshwater bacterial communities. Microorganisms resistant to commonly prescribed antibiotics (superbug) have dramatically increased over the last decades. The presence of antibiotics in waters, in food and beverages in both their un-metabolized and metabolized forms are of interest for humans. This is due to daily exposure in small quantities, that, when accumulated, could lead to development of drug resistance to antibiotics, or multiply the risk of allergic reaction. Conventional analytical methods used to quantify antibiotics are relatively expensive and generally require long analysis time associated with the difficulties to perform field analyses. In this context, electrochemical and optical based sensing devices are of interest, offering great potentials for a broad range of analytical applications. This review will focus on the application of magnetic nanoparticles in the design of different analytical methods, mainly sensors, used for the detection of antibiotics in different matrices (human fluids, the environmental, food and beverages samples).
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