Complete 1H and 13C NMR spectral assignment of α- and β-adenosine, 2'-deoxyadenosine and their acetate derivatives

被引：75
作者：
Ciuffreda, P.
Casatii, S.
Manzocchi, A.
机构：
[1] Univ Milan, Dipartmento Chim Biochim & Biotecnol Med, I-20133 Milan, Italy
[2] Univ Milan, Dipartimento Sci Preclin LITA Vialba, I-20157 Milan, Italy
来源：
MAGNETIC RESONANCE IN CHEMISTRY | 2007年 / 45卷 / 09期
关键词：
H-1; NMR; C-13; gCOSY; gNOESY; gHSQC; gHMBC; beta- and alpha-adenine nucleosides; beta- and alpha-adenine nucleoside acetates;
D O I：
10.1002/mrc.2036
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
H-1 and C-13 NMR chemical shifts of alpha- and beta-anomers of adenosine, 2'-deoxyadenosine and their acetate derivatives were completely and definitely assigned using the concerted application of one- and two-dimensional experiments (gCOSY, gNOESY, gHSQC and gHMBC). The influence of the stereochemistry of the purine base on the NMR data of the hydrogen and carbon atoms of the furanose moiety was estimated. Copyright (C) 2007 John Wiley & Sons, Ltd.
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页码：781 / 784
页数：4
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