Introducing an Electrochemical Sensor Based on Two Layers of Ag Nanoparticles Decorated Graphene for Rapid Determination of Methadone in Human Blood Serum

被引:35
作者
Baghayeri, Mehdi [1 ]
Nabavi, Samaneh [2 ]
Hasheminejad, Ehteram [3 ]
Ebrahimi, Vida [1 ]
机构
[1] Hakim Sabzevari Univ, Fac Sci, Dept Chem, POB 397, Sabzevar, Iran
[2] Res Inst Police Sci & Social Studies, POB 19395-6516, Tehran, Iran
[3] Islamic Azad Univ, Sabzevar Branch, Young Researchers & Elite Club, Sabzevar, Iran
关键词
Methadone; Graphene; Ag nanoparticles; Nanocomposite; Biological samples; LIQUID-LIQUID MICROEXTRACTION; SILVER NANOPARTICLES; ELECTROCATALYTIC ACTIVITY; SENSITIVE DETERMINATION; SELECTIVE DETERMINATION; GOLD NANOSTRUCTURE; BIOLOGICAL SAMPLES; ELECTRODE; DRUGS; ABUSE;
D O I
10.1007/s11244-021-01483-4
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
In the present study, a highly efficient electrochemical sensor for methadone measurement through the use of a glassy carbon electrode modified with two layers of graphene/Ag nanoparticles ((Gr/AgNPs)(2)/GCE) nanocomposite is introduced. The morphological, elemental and electrochemical properties of the as-prepared nanocomposite were evaluated by scanning electron microscopy, energy dispersive spectroscopy. The influence of different experimental parameters such as pH and scan rate on the voltammetric response of methadone was also addressed. Exhibiting a peak potential at + 0.79 V (vs. Ag/AgCl), the as-prepared electrode manifested an improvement in its catalytic activity toward methadone oxidation. Under optimal conditions, the developed sensor exhibited an excellent response toward methadone in the concentration range of 1.0-200.0 mu M with a detection limit of 0.12 mu M. Moreover, the proposed electrode offered superior selectivity for methadone reflecting its efficiency for the real samples such as human blood serum.
引用
收藏
页码:623 / 632
页数:10
相关论文
共 55 条
  • [21] Electrochemical immunosensor development based on core-shell high-crystalline graphitic carbon nitride@carbon dots and Cd0.5Zn0.5S/d-Ti3C2Tx MXene composite for heart-type fatty acid-binding protein detection
    Karaman, Ceren
    Karaman, Onur
    Atar, Necip
    Yola, Mehmet Lutfi
    [J]. MICROCHIMICA ACTA, 2021, 188 (06)
  • [22] Orange Peel Derived-Nitrogen and Sulfur Co-doped Carbon Dots: a Nano-booster for Enhancing ORR Electrocatalytic Performance of 3D Graphene Networks
    Karaman, Ceren
    [J]. ELECTROANALYSIS, 2021, 33 (05) : 1356 - 1369
  • [23] Karim-Nezhad G, 2017, ANAL BIOANAL ELECTRO, V9, P689
  • [24] A critical review on the use of potentiometric based biosensors for biomarkers detection
    Karimi-Maleh, Hassan
    Orooji, Yasin
    Karimi, Fatemeh
    Alizadeh, Marzieh
    Baghayeri, Mehdi
    Rouhi, Jalal
    Tajik, Somayeh
    Beitollahi, Hadi
    Agarwal, Shilpi
    Gupta, Vinod K.
    Rajendran, Saravanan
    Ayati, Ali
    Fu, Li
    Sanati, Afsaneh L.
    Tanhaei, Bahareh
    Sen, Fatih
    Shabani-nooshabadi, Mehdi
    Asrami, Padideh Naderi
    Al-Othman, Amani
    [J]. BIOSENSORS & BIOELECTRONICS, 2021, 184 (184)
  • [25] Guanine-Based DNA Biosensor Amplified with Pt/SWCNTs Nanocomposite as Analytical Tool for Nanomolar Determination of Daunorubicin as an Anticancer Drug: A Docking/Experimental Investigation
    Karimi-Maleh, Hassan
    Alizadeh, Marzieh
    Orooji, Yasin
    Karimi, Fatemeh
    Baghayeri, Mehdi
    Rouhi, Jalal
    Tajik, Somayeh
    Beitollahi, Hadi
    Agarwal, Shilpi
    Gupta, Vinod K.
    Rajendran, Saravanan
    Rostamnia, Sadegh
    Fu, Li
    Saberi-Movahed, Farshad
    Malekmohammadi, Samira
    [J]. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 2021, 60 (02) : 816 - 823
  • [26] A novel detection method for organophosphorus insecticide fenamiphos: Molecularly imprinted electrochemical sensor based on core-shell Co3O4@MOF-74 nanocomposite
    Karimi-Maleh, Hassan
    Yola, Mehmet Lutfi
    Atar, Necip
    Orooji, Yasin
    Karimi, Fatemeh
    Kumar, P. Senthil
    Rouhi, Jalal
    Baghayeri, Mehdi
    [J]. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 2021, 592 : 174 - 185
  • [27] A new nickel-based co-crystal complex electrocatalyst amplified by NiO dope Pt nanostructure hybrid; a highly sensitive approach for determination of cysteamine in the presence of serotonin
    Karimi-Maleh, Hassan
    Karimi, Fatemeh
    Orooji, Yasin
    Mansouri, Ghobad
    Razmjou, Amir
    Aygun, Aysenur
    Sen, Fatih
    [J]. SCIENTIFIC REPORTS, 2020, 10 (01)
  • [28] Palladium-Nickel nanoparticles decorated on Functionalized-MWCNT for high precision non-enzymatic glucose sensing
    Karimi-Maleh, Hassan
    Cellat, Kemal
    Arikan, Kubilay
    Savk, Aysun
    Karimi, Fatemeh
    Sen, Fatih
    [J]. MATERIALS CHEMISTRY AND PHYSICS, 2020, 250
  • [29] An amplified voltammetric sensor based on platinum nanoparticle/polyoxometalate/two-dimensional hexagonal boron nitride nanosheets composite and ionic liquid for determination of N-hydroxysuccinimide in water samples
    Karimi-Maleh, Hassan
    Karimi, Fatemeh
    Malekmohammadi, Samira
    Zakariae, Nilofar
    Esmaeili, Roghayeh
    Rostamnia, Sadegh
    Yola, Mehmet Lutfi
    Atar, Necip
    Movaghgharnezhad, Shirin
    Rajendran, Saravanan
    Razmjou, Amir
    Orooji, Yasin
    Agarwal, Shilpi
    Gupta, Vinod Kumar
    [J]. JOURNAL OF MOLECULAR LIQUIDS, 2020, 310
  • [30] Electrochemical Sensors, a Bright Future in the Fabrication of Portable Kits in Analytical Systems
    Karimi-Maleh, Hassan
    Karimi, Fatemeh
    Alizadeh, Marzieh
    Sanati, Afsaneh L.
    [J]. CHEMICAL RECORD, 2020, 20 (07) : 682 - 692