Suspicion Is Key: Diagnosing Elusive Cytoplasmic Antineutrophil Cytoplasmic Antibody (c-ANCA)-Positive Vasculitis

被引：0

作者：

Crowe, Timothy P. ^{[1
]}

Campos, Roberto ^{[1
]}

Pereira-Duque, Juan ^{[2
]}

Samiullah, Mohammad ^{[2
]}

Eftikari, Perham ^{[3
]}

机构：

[1] Nova Southeastern Univ, Dr Kiran C Patel Coll Osteopath Med, Internal Med, Ft Lauderdale, FL 33314 USA

[2] Broward Hlth Gen, Internal Med, Ft Lauderdale, FL USA

[3] Broward Hlth Gen, Nephrol, Ft Lauderdale, FL USA

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2022年 / 14卷 / 05期

关键词：

antineutrophil; glomerulonephritis; vasculitis; myeloperoxidase; anca;

D O I：

10.7759/cureus.25501

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We present a case of a 53-year-old black male with a past medical history of type 2 diabetes presenting with fatigue, generalized myalgias, and unintentional weight loss developed over several months. The patient was diagnosed with cytoplasmic antineutrophil cytoplasmic antibody (c-ANCA)-positive vasculitis. Renal biopsy confirmed antineutrophil cytoplasmic antibody (ANCA) crescentic necrotizing glomerulonephritis. c-ANCA was positive by enzyme-linked immunosorbent assay. Anti-myeloperoxidase antibody was positive. Without paranasal or lung involvement, the diagnosis was made of renal-limited necrotizing and crescentic glomerulonephritis. The patient was treated with rituximab and prednisone therapy.

引用

页数：7

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