Suspicion Is Key: Diagnosing Elusive Cytoplasmic Antineutrophil Cytoplasmic Antibody (c-ANCA)-Positive Vasculitis

被引:0
作者
Crowe, Timothy P. [1 ]
Campos, Roberto [1 ]
Pereira-Duque, Juan [2 ]
Samiullah, Mohammad [2 ]
Eftikari, Perham [3 ]
机构
[1] Nova Southeastern Univ, Dr Kiran C Patel Coll Osteopath Med, Internal Med, Ft Lauderdale, FL 33314 USA
[2] Broward Hlth Gen, Internal Med, Ft Lauderdale, FL USA
[3] Broward Hlth Gen, Nephrol, Ft Lauderdale, FL USA
关键词
antineutrophil; glomerulonephritis; vasculitis; myeloperoxidase; anca;
D O I
10.7759/cureus.25501
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We present a case of a 53-year-old black male with a past medical history of type 2 diabetes presenting with fatigue, generalized myalgias, and unintentional weight loss developed over several months. The patient was diagnosed with cytoplasmic antineutrophil cytoplasmic antibody (c-ANCA)-positive vasculitis. Renal biopsy confirmed antineutrophil cytoplasmic antibody (ANCA) crescentic necrotizing glomerulonephritis. c-ANCA was positive by enzyme-linked immunosorbent assay. Anti-myeloperoxidase antibody was positive. Without paranasal or lung involvement, the diagnosis was made of renal-limited necrotizing and crescentic glomerulonephritis. The patient was treated with rituximab and prednisone therapy.
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页数:7
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