UGT1A1 and UGT1A9 variants affect thyroxine glucuronidation in human livers.

被引:0
|
作者
Graber, AY [1 ]
Innocenti, F [1 ]
Ramirez, J [1 ]
Chen, PX [1 ]
Das, S [1 ]
Ratain, MJ [1 ]
机构
[1] Univ Chicago, Chicago, IL 60637 USA
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:P73 / P73
页数:1
相关论文
共 50 条
  • [21] Role of HNF-1A in the regulation of UGT1A1, UGT1A9 and UGT2B7 MRNA expression.
    Mirkov, S
    Innocenti, F
    Liu, W
    Chen, PX
    Ramirez, J
    Undevia, SD
    Das, S
    Ratain, MJ
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2005, 77 (02) : P61 - P61
  • [22] Glucuronidation of piceatannol by human liver microsomes: major role of UGT1A1, UGT1A8 and UGT1A10
    Miksits, Michaela
    Maier-Salamon, Alexandra
    Thanh Phuong Nha Vo
    Sulyok, Michael
    Schuhmacher, Rainer
    Szekeres, Thomas
    Jaeger, Walter
    JOURNAL OF PHARMACY AND PHARMACOLOGY, 2010, 62 (01) : 47 - 54
  • [23] Inhibition of UGT1A1*1 and UGT1A1*6 catalyzed glucuronidation of SN-38 by silybins
    Li, Wei
    Chen, Yin-Nan
    Chen, Yue-Yue
    Wang, Zhe
    Wang, Zhen
    Jiang, Li-Li
    Shi, Hong-Can
    Liu, Yong
    CHEMICO-BIOLOGICAL INTERACTIONS, 2022, 368
  • [24] Hepatocyte nuclear factor-1 alpha is associated with UGT1A1, UGT1A9 and UGT2B7 mRNA expression in human liver
    Ramirez, J.
    Mirkov, S.
    Zhang, W.
    Chen, P.
    Das, S.
    Liu, W.
    Ratain, M. J.
    Innocenti, F.
    PHARMACOGENOMICS JOURNAL, 2008, 8 (02): : 152 - 161
  • [25] Hepatocyte nuclear factor-1 alpha is associated with UGT1A1, UGT1A9 and UGT2B7 mRNA expression in human liver
    J Ramírez
    S Mirkov
    W Zhang
    P Chen
    S Das
    W Liu
    M J Ratain
    F Innocenti
    The Pharmacogenomics Journal, 2008, 8 : 152 - 161
  • [26] Predictive Role of the UGT1A1, UGT1A7, and UGT1A9 Genetic Variants and Their Haplotypes on the Outcome of Metastatic Colorectal Cancer Patients Treated With Fluorouracil, Leucovorin, and Irinotecan
    Cecchin, Erika
    Innocenti, Federico
    D'Andrea, Mario
    Corona, Giuseppe
    De Mattia, Elena
    Biason, Paola
    Buonadonna, Angela
    Toffoli, Giuseppe
    JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (15) : 2457 - 2465
  • [27] Glucuronidation of 1-hydroxypyrene by human liver microsomes and human UDP-glucuronosyltransferases UGT1A6, UGT1A7, and UGT1A9: Development of a high-sensitivity glucuronidation assay for human tissue
    Luukkanen, L
    Mikkola, J
    Forsman, T
    Taavitsainen, P
    Taskinen, J
    Elovaara, E
    DRUG METABOLISM AND DISPOSITION, 2001, 29 (08) : 1096 - 1101
  • [28] Effects of coexpression of UGT1A9 on enzymatic activities of human UGT1A isoforms
    Fujiwara, Ryoichi
    Nakajima, Miki
    Yamanaka, Hiroyuki
    Nakamura, Akiko
    Katoh, Miki
    Ikushiro, Shin-ichi
    Sakaki, Toshiyuki
    Yokoi, Tsuyoshi
    DRUG METABOLISM AND DISPOSITION, 2007, 35 (05) : 747 - 757
  • [29] Hepatocyte nuclear factor-1 alpha is associated with UGT1A1, UGT1A9 and UGT2B7 mRNA expression in human liver.
    Mirkov, S.
    Ramirez, J.
    Zhang, W.
    Chen, P.
    Das, S.
    Liu, W.
    Ratain, M. J.
    Innocenti, F.
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2007, 81 : S61 - S61
  • [30] Interactions between human UGT1A1, UGT1A4, and UGT1A6 affect their enzymatic activities
    Fujiwara, Ryoichi
    Nakajima, Miki
    Yamanaka, Hiroyuki
    Katoh, Miki
    Yokoi, Tsuyoshi
    DRUG METABOLISM AND DISPOSITION, 2007, 35 (10) : 1781 - 1787