UGT1A1 and UGT1A9 variants affect thyroxine glucuronidation in human livers.

被引:0
|
作者
Graber, AY [1 ]
Innocenti, F [1 ]
Ramirez, J [1 ]
Chen, PX [1 ]
Das, S [1 ]
Ratain, MJ [1 ]
机构
[1] Univ Chicago, Chicago, IL 60637 USA
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:P73 / P73
页数:1
相关论文
共 50 条
  • [1] Influence of genetic variants in UGT1A1 and UGT1A9 on the in vivo glucuronidation of SN-38.
    Singh, A
    Paoluzzi, L
    Price, D
    Danesi, R
    Mathijssen, RH
    Verweij, J
    Figg, WD
    Sparreboom, A
    JOURNAL OF CLINICAL ONCOLOGY, 2004, 22 (14) : 145S - 145S
  • [2] Influence of genetic variants in UGT1A1 and UGT1A9 on the in vivo glucuronidation of SN-38
    Paoluzzi, L
    Singh, AS
    Price, DK
    Danesi, R
    Mathijssen, RHJ
    Verweij, J
    Figg, WD
    Sparreboom, A
    JOURNAL OF CLINICAL PHARMACOLOGY, 2004, 44 (08): : 854 - 860
  • [3] UGT1A1*28 genotype affects the in-vitro glucuronidation of thyroxine in human livers
    Graber, Andrea L. Yoder
    Ramirez, Jacqueline
    Innocenti, Federico
    Ratain, Mark J.
    PHARMACOGENETICS AND GENOMICS, 2007, 17 (08): : 619 - 627
  • [4] Raloxifene glucuronidation in liver and intestinal microsomes of humans and monkeys: contribution of UGT1A1, UGT1A8 and UGT1A9
    Kishi, Naoki
    Takasuka, Akane
    Kokawa, Yuki
    Isobe, Takashi
    Taguchi, Maho
    Shigeyama, Masato
    Murata, Mikio
    Suno, Manabu
    Hanioka, Nobumitsu
    XENOBIOTICA, 2016, 46 (04) : 289 - 295
  • [5] Glucuronidation of flavonoids by recombinant UGT1A3 and UGT1A9
    Chen, Yakun
    Xie, Shenggu
    Chen, Shuqing
    Zeng, Su
    BIOCHEMICAL PHARMACOLOGY, 2008, 76 (03) : 416 - 425
  • [6] Sorafenib Is an Inhibitor of UGT1A1 but Is Metabolized by UGT1A9: Implications of Genetic Variants on Pharmacokinetics and Hyperbilirubinemia
    Peer, Cody J.
    Sissung, Tristan M.
    Kim, AeRang
    Jain, Lokesh
    Woo, Sukyung
    Gardner, Erin R.
    Kirkland, C. Tyler
    Troutman, Sarah M.
    English, Bevin C.
    Richardson, Emily D.
    Federspiel, Joel
    Venzon, David
    Dahut, William
    Kohn, Elise
    Kummar, Shivaani
    Yarchoan, Robert
    Giaccone, Giuseppe
    Widemann, Brigitte
    Figg, William D.
    CLINICAL CANCER RESEARCH, 2012, 18 (07) : 2099 - 2107
  • [7] Glucuronidation of flavonoids by human UGT1A3, UGT1A9 and structure-activity relationships
    Xie, Shenggu
    Chen, Yakun
    Chen, Shuqing
    Zeng, Su
    DRUG METABOLISM REVIEWS, 2006, 38 : 129 - 129
  • [8] Differences in UGT1A1, UGT1A7, and UGT1A9 Polymorphisms between Uzbek and Japanese Populations
    Hiromichi Maeda
    Shoichi Hazama
    Abdiev Shavkat
    Ken Okamoto
    Koji Oba
    Junichi Sakamoto
    Kenichi Takahashi
    Masaki Oka
    Daisuke Nakamura
    Ryouichi Tsunedomi
    Naoko Okayama
    Hideyuki Mishima
    Michiya Kobayashi
    Molecular Diagnosis & Therapy, 2014, 18 : 333 - 342
  • [9] Differences in UGT1A1, UGT1A7, and UGT1A9 Polymorphisms between Uzbek and Japanese Populations
    Maeda, Hiromichi
    Hazama, Shoichi
    Shavkat, Abdiev
    Okamoto, Ken
    Oba, Koji
    Sakamoto, Junichi
    Takahashi, Kenichi
    Oka, Masaki
    Nakamura, Daisuke
    Tsunedomi, Ryouichi
    Okayama, Naoko
    Mishima, Hideyuki
    Kobayashi, Michiya
    MOLECULAR DIAGNOSIS & THERAPY, 2014, 18 (03) : 333 - 342
  • [10] UGT1A1 and UGT1A9 Are Responsible for Phase II Metabolism of Tectorigenin and Irigenin In Vitro
    Li, Ji
    Xu, Zhangyao
    Gu, Jifeng
    MOLECULES, 2022, 27 (13):