Water-soluble acetylated chitosan-stabilized gold nanosphere bioprobes

被引：4

作者：

Le, Lanh T. ^{[1
]}

Hai-Phong Nguyen ^{[2
]}

Quang-Khieu Dinh ^{[2
]}

Thai-Long Hoang ^{[2
]}

Quoc-Hien Nguyen ^{[3
]}

Thai-Hoa Tran ^{[2
]}

Thanh-Dinh Nguyen ^{[4
]}

机构：

[1] Tech & Econ Coll Quang Nam, Quang Nam, Vietnam

[2] Hue Univ, Dept Chem, Coll Sci, Hue, Vietnam

[3] Vietnam Atom Energy Inst, Res & Dev Ctr Radiat Technol, Ho Chi Minh City, Vietnam

[4] Univ British Columbia, Dept Chem, Vancouver, BC V6T 1Z1, Canada

来源：

MATERIALS CHEMISTRY AND PHYSICS | 2015年 / 149卷

基金：

加拿大自然科学与工程研究理事会;

关键词：

Gold; Nanostructure; Surfactant-assisted synthesis; Electrochemical measurements; Optical properties; SURFACE-PLASMON RESONANCE; METAL NANOCRYSTALS; SIZE DISTRIBUTION; VISUAL DETECTION; LABEL-FREE; URIC-ACID; NANOPARTICLES; NANOSTRUCTURES; MELAMINE; CHITIN;

D O I：

10.1016/j.matchemphys.2014.10.024

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Sustainable biopolymers are intriguing motifs for transferring the distinct biocompatibility and recognition into inorganic nanoparticles, which have a potential to be used in biomedicine applications. Here we report scalable production of water-soluble chitosan polymers from N-acetylation. One-pot aqueous synthesis of water-dispersible gold nanospheres is developed using the acetylated chitosan as a stabilizer and a reducing agent. The inherent aqueous solubility of the acetylated chitosan renders the gold nanospheres dispersible in water and enables for controlling the uniform size and monodispersity. The acetylated chitosan-stabilized gold nanospheres with plasmonic and biocompatible properties are used as efficient bioprobes for the selective detection of various biochemical agents of melamine, bacteria, and uric acid. (C) 2014 Elsevier B.V. All rights reserved.

引用

页码：324 / 332

页数：9

共 55 条

[1] Raman Imaging in Biochemical and Biomedical Applications. Diagnosis and Treatment of Breast Cancer [J].