The fabrication of nanocomposites using the nanostructure of segmented polyurethanes (PU) as a template was investigated. Inorganic moieties were incorporated into polyurethanes having different segmented chain configurations to yield a variety of nanostructured materials. The microphase separation process in pure polyurethane is found to reproduce in PU modified with inorganic species. The results show that the natural self-assembly and well-controlled nanostructures of segmented PU can be used as a template in the preparation of nanocomposites that can be use to in the fabrication of advanced devices.