Headache and CNS white matter abnormalities associated with gluten sensitivity

被引：92
作者：
Hadjivassiliou, M
Grünewald, RA
Lawden, M
Davies-Jones, GAB
Powell, T
Smith, CML
机构：
[1] Royal Hallamshire Hosp, Dept Clin Neurol, Sheffield S10 2JF, S Yorkshire, England
[2] Royal Hallamshire Hosp, Dept Neuroradiol & Neuropathol, Sheffield S10 2JF, S Yorkshire, England
[3] Leicester Royal Infirm, Dept Clin Neurol, Leicester, Leics, England
来源：
NEUROLOGY | 2001年 / 56卷 / 03期
关键词：
D O I：
10.1212/WNL.56.3.385
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
The authors describe 10 patients with gluten sensitivity and abnormal MRI. All experienced episodic headache, six had unsteadiness, and four had gait ataxia. MRI abnormalities varied from confluent areas of high signal throughout the white matter to foci of high signal scattered in both hemispheres. Symptomatic response to gluten-free diet was seen in nine patients.
引用
收藏
页码：385 / 388
页数：4
相关论文
共 10 条
[1]   Cerebral involvement in celiac disease: A serial MRI study in a patient with brainstem and cerebellar symptoms [J].
Ghezzi, A ;
Filippi, M ;
Falini, A ;
Zaffaroni, M .
NEUROLOGY, 1997, 49 (05) :1447-1450
[2]   Gluten sensitivity:: a many headed hydra -: Heightened responsiveness to gluten is not confined to the gut [J].
Hadjivassiliou, M ;
Grünewald, RA ;
Davies-Jones, GAB .
BMJ-BRITISH MEDICAL JOURNAL, 1999, 318 (7200) :1710-1711
[3]   Clinical, radiological, neurophysiological, and neuropathological characteristics of gluten ataxia [J].
Hadjivassiliou, M ;
Grünewald, R ;
Chattopadhyay, AK ;
Davies-Jones, GAB ;
Gibson, A ;
Jarratt, JA ;
Kandler, RH ;
Lobo, A ;
Powell, T ;
Smith, CML .
LANCET, 1998, 352 (9140) :1582-1585
[4]  
Hadjivassiliou M, 1999, J NEUROL NEUROSUR PS, V67, P257, DOI 10.1136/jnnp.67.2.257
[5]   Does cryptic gluten sensitivity play a part in neurological illness? [J].
Hadjivassiliou, M ;
Gibson, A ;
DaviesJones, GAB ;
Lobo, AJ ;
Stephenson, TJ ;
MilfordWard, A .
LANCET, 1996, 347 (8998) :369-371
[6]  
Holmes GKT, 1997, EPILEPSY AND OTHER NEUROLOGICAL DISORDERS IN COELIAC DISEASE, P251
[7]  
MARSH MN, 1995, QJM-MON J ASSOC PHYS, V88, P9
[8]   Progressive ataxia, focal seizures, and malabsorption syndrome in a 41 year old woman [J].
Mumford, CJ ;
Fletcher, NA ;
Ironside, JW ;
Warlow, CP .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1996, 60 (02) :225-230
[9]   ISOLATED VASCULITIS OF THE CENTRAL-NERVOUS-SYSTEM IN A PATIENT WITH CELIAC-DISEASE [J].
RUSH, PJ ;
INMAN, R ;
BERNSTEIN, M ;
CARLEN, P ;
RESCH, L .
AMERICAN JOURNAL OF MEDICINE, 1986, 81 (06) :1092-1094
[10]   Migraine and coeliac disease [J].
Serratrice, J ;
Disdier, P ;
de Roux, C ;
Christides, C ;
Weiller, PJ .
HEADACHE, 1998, 38 (08) :627-628
1