Role of Nitric Oxide in Activity Control of Mechanically Gated Ionic Channels in Cardiomyocytes: NO-Donor Study

被引：7

作者：

Kazanski, V. E. ^{[1
]}

Kamkin, A. G. ^{[1
]}

Makarenko, E. Yu. ^{[1
]}

Lysenko, N. N. ^{[1
]}

Sutiagin, P. V. ^{[2
]}

Bo, Tian ^{[1
]}

Kiseleva, I. S. ^{[1
]}

机构：

[1] NI Pirogov Russian State Med Univ, Medicobiol Fac, Dept Fundamental & Appl Physiol, Moscow, Russia

[2] NI Pirogov Russian State Med Univ, Medicobiol Fac, Dept Morphol, Moscow, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2010年 / 150卷 / 01期

基金：

俄罗斯基础研究基金会;

关键词：

isolated cardiomyocytes; whole-cell ionic currents; mechanically gated channels; NO-donors; VENTRICULAR MYOCYTES; MYOCARDIAL-FUNCTION; MEMBRANE CURRENTS; STRETCH;

D O I：

10.1007/s10517-010-1052-7

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Whole-cell ionic currents through mechanically gated chnnels (MGC) were recorded in isolated cardiomyocytes under voltage clamp conditions. In unstrained cells, NO donors SNAP and DEA-NO activated MGC and induced MG-like currents. In contrast, in stretched cells with activated MGC, these NO-donors inactivated and inhibited MGC.

引用

页码：1 / 5

页数：5

共 39 条

[21] Evaluation of the role of nitric oxide and antioxidation in the antiulcer activity of Ocimum sanctum leaves: an experimental study
Bhajoni P.S.
Meshram G.G.
Lahkar M.
Ghadlinge M.S.
Rehan H.S.
Tripathi C.D.
Oriental Pharmacy and Experimental Medicine, 2015, 15 (4): : 313 - 317
[22] Studying the Role of Alveolar Exhaled Nitric Oxide in Combination with Bronchial Nitric Oxide to Predict Asthma Control in Children with Asthma: A Real-Life Prospective Study
Nguyen-Thi-Dieu, Thuy
Do-Thi, Hanh
Nguyen-Thi-Quynh, Huong
Le-Thi-Minh, Huong
Duong-Quy, Sy
CURRENT RESPIRATORY MEDICINE REVIEWS, 2023, 19 (01) : 66 - 76
[23] Role of the nitric oxide/cyclic GMP pathway and extracellular environment in the nitric oxide donor-induced increase in dopamine secretion from PC12 cells:: a microdialysis in vitro study
Serra, PA
Rocchitta, G
Delogu, MR
Migheli, R
Taras, MG
Mura, MP
Esposito, G
Miele, E
Desole, MS
Miele, M
JOURNAL OF NEUROCHEMISTRY, 2003, 86 (06) : 1403 - 1413
[24] Role of angiotensin AT2 receptors and nitric oxide in the cardiopulmonary baroreflex control of renal sympathetic nerve activity in rats
Abdulla, Mohammed H.
Johns, Edward J.
JOURNAL OF HYPERTENSION, 2013, 31 (09) : 1837 - 1846
[25] The potential role of inducible nitric oxide synthase (iNOS) activity in the testicular dysfunction associated with varicocele: An experimental study
İsmail Türker Köksal
Tibet Erdoğru
Hakan Gülkesen
Cem Sezer
Mustafa Usta
Akif Çiftçioğlu
Mehmet Baykara
International Urology and Nephrology, 2003, 36 (1) : 67 - 72
[26] The potential role of inducible nitric oxide synthase (iNOS) activity in the testicular dysfunction associated with varicocele: An experimental study
Koksal, Ismail Tuerker
Erdogru, Tibet
Gulkesen, Hakan
Sezer, Cem
Usta, Mustafa
Ciftcioglu, Akif
Baykara, Mehmet
INTERNATIONAL UROLOGY AND NEPHROLOGY, 2003, 36 (01) : 67 - 72
[27] Study of interaction between nitric oxide and ACE activity in STZ-induced diabetic rats: role of insulin
Sharifi, AM
Mousavi, SH
Larijani, A
PHARMACOLOGICAL RESEARCH, 2004, 50 (03) : 261 - 266
[28] The role of blood nitric oxide level in predicting return of spontaneous circulation: a prospective case-control study
Bayramoglu, Atif
Tekin, Erdal
Kurt, Engin
Kasali, Kamber
Kurt, Nezahat
REVISTA DA ASSOCIACAO MEDICA BRASILEIRA, 2024, 70 (08):
[29] Nitric Oxide Concentrations Are Normal and Unrelated to Activity Level in Chronic Fatigue Syndrome: A Case-Control Study
Meeus, Mira
Van Eupen, Inge
Hondequin, Jasmien
De Hauwere, Lieve
Kos, Daphne
Nijs, Jo
IN VIVO, 2010, 24 (06): : 865 - 869
[30] Role of metformin in endothelial dysfunction: a randomized control trial study by using nitric oxide and flow mediated dilation measurement
Aji, K. Bayu
Wasyanto, T.
EUROPEAN HEART JOURNAL SUPPLEMENTS, 2017, 19 (0E) : E20 - E20

← 1 2 3 4 →