A Novel Use of Romiplostim for SARS-CoV-2-induced Thrombocytopenia

被引：4
|
作者：
Schneider, Coursen W. [1 ]
Penney, Scott W. [2 ]
Helfrich, Alison M. [3 ]
Hartman, Kip R. [2 ]
Lieuw, Kenneth [2 ]
机构：
[1] Walter Reed Natl Mil Med Ctr, Dept Pediat, Bethesda, MD USA
[2] Walter Reed Natl Mil Med Ctr, Dept Pediat Hematol Oncol, 4493 North Palmer Rd, Bethesda, MD 20889 USA
[3] Walter Reed Natl Mil Med Ctr, Dept Pediat Infect Dis, Bethesda, MD USA
来源：
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY | 2021年 / 43卷 / 06期
关键词：
coronavirus disease of 2019 (COVID-19); severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); thrombocytopenia; thrombopoetin receptor agonist; IMMUNE THROMBOCYTOPENIA; DOUBLE-BLIND; CHILDREN; PHASE-3;
D O I：
10.1097/MPH.0000000000001961
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The literature regarding coronavirus disease of 2019 (COVID-19) infection in pediatrics indicates that children have less severe clinical presentations and lower mortality rates. There remains limited data regarding hematologic sequelae in pediatric patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Romiplostim has shown a platelet response in pediatric patients with chronic immune thrombocytopenic purpura, and eltrombopag is proven to increase platelet counts in patients with inherited thrombocytopenia. We review SARS-CoV-2-associated thrombocytopenia and present a pediatric patient with acute on chronic thrombocytopenia in the setting of COVID-19 with subsequent platelet recovery using romiplostim.
引用
收藏
页码：E788 / E790
页数：3
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