Subclinical leaflet thrombosis following transcatheter aortic valve replacement

被引:27
|
作者
Kanjanauthai, Somsupha [1 ]
Pirelli, Luigi [1 ]
Nalluri, Nikhil [2 ]
Kliger, Chad A. [1 ]
机构
[1] Lenox Hill Heart & Lung, 130 East 77th St,Suite 4th Floor, New York, NY 10075 USA
[2] Staten Isl Univ Hosp, Valve & Struct Heart Ctr, New York, NY USA
关键词
hypoattenuated leaflet thickening; hypoattenuation affecting motion; leaflet thrombosis; reduced leaflet motion; transcatheter aortic valve replacement; transcatheter heart valve thrombosis; BIOPROSTHETIC VALVE; BLOOD STASIS; IMPLANTATION; OUTCOMES; SOCIETY; TAVR; ECHOCARDIOGRAPHY; PREDICTORS; FAILURE; RISK;
D O I
10.1111/joic.12521
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Since the inception of transcatheter aortic valve replacement (TAVR), there have been significant reductions in complications due to improvements of transcatheter heart valve (THV) designs and technologies. Given expanding TAVR applications, reducing complications further and better understanding THV durability has become a focus within the structural heart space. Recently, dedicated cardiac computed tomographic angiography (CTA) performed at 1 month post-TAVR has identified subclinical leaflet thrombosis (SLT), with rates as high as 40%. From the SLT imaging hallmarks of hypoattenuated leaflet thickening (HALT) to hypoattenuation affecting motion (HAM), a postulated timeline of THV thrombosis advancing to clinical symptoms can be recognized. This review article focuses on leaflet thrombosis particularly following TAVR explaining the spectrum of this disease process, its diagnosis, current treatment options, and future directions in the field.
引用
收藏
页码:640 / 647
页数:8
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