MetaFluxNet: the management of metabolic reaction information and quantitative metabolic flux analysis

被引：92

作者：

Lee, DY

Yun, H

Park, S

Lee, SY

机构：

[1] Korea Adv Inst Sci & Technol, Metab Biomol Engn Natl Res Lab, Taejon 305701, South Korea

[2] Korea Adv Inst Sci & Technol, Dept Chem & Biomol Engn, Taejon 305701, South Korea

[3] Korea Adv Inst Sci & Technol, Bioproc Engn Res Ctr, Taejon 305701, South Korea

[4] Korea Adv Inst Sci & Technol, Dept Biosyst, Taejon 305701, South Korea

[5] Korea Adv Inst Sci & Technol, Bioinformat Res Ctr, Taejon 305701, South Korea

来源：

BIOINFORMATICS | 2003年 / 19卷 / 16期

关键词：

D O I：

10.1093/bioinformatics/btg271

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

MetaFluxNet is a program package for managing information on the metabolic reaction network and for quantitatively analyzing metabolic fluxes in an interactive and customized way. It allows users to interpret and examine metabolic behavior in response to genetic and/or environmental modifications. As a result, quantitative in silico simulations of metabolic pathways can be carried out to understand the metabolic status and to design the metabolic engineering strategies. The main features of the program include a well-developed model construction environment, user-friendly interface for metabolic flux analysis (MFA), comparative MFA of strains having different genotypes under various environmental conditions, and automated pathway layout creation.

引用

页码：2144 / 2146

页数：3

共 4 条

[1]

[Anonymous], 1999, METABOLIC ENG

[2] FluxAnalyzer: exploring structure, pathways, and flux distributions in metabolic networks on interactive flux maps [J].