SnCl2•2H2O-catalyzed efficient synthesis of β-acetamido ketones and β-acetamido ketoesters under solvent-free conditions

被引：40

作者：

Nagarapu, Lingaiah ^{[1
]}

Bantu, Rajashaker ^{[1
]}

Puttireddy, Rakesh ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Div Organ Chem 3, Hyderabad 500007, Andhra Pradesh, India

来源：

APPLIED CATALYSIS A-GENERAL | 2007年 / 332卷 / 02期

关键词：

one-pot synthesis; beta-acetamido ketones; beta-acetamido ketoesters; enolisable ketones; simple procedure;

D O I：

10.1016/j.apcata.2007.08.033

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

SnCl2 center dot H2O has been found to be useful and highly efficient for the preparation of beta-acetamido ketones and beta-acetamido ketoesters by a one-pot reaction of aryl aldehydes, enolisable ketones, acetyl chloride and acetonitrile in a solvent-free media at room temperature. The present methodology offers several advantages such as excellent yields, simple procedure, short reaction times (1-2.5 h) and milder conditions. (c) 2007 Elsevier B.V. All rights reserved.

引用

页码：304 / 309

页数：6

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