Viral infection and atherosclerosis

被引：40

作者：

Hemmat, Nima ^{[1
,2
]}

Ebadi, Amin ^{[1
,2
]}

Badalzadeh, Reza ^{[3
,4
]}

Memar, Mohammad Yousef ^{[2
]}

Baghi, Hossein Bannazadeh ^{[1
,2
,5
]}

机构：

[1] Tabriz Univ Med Sci, Immunol Res Ctr, Tabriz, Iran

[2] Tabriz Univ Med Sci, Infect & Trop Dis Res Ctr, POB 5165665931, Tabriz, Iran

[3] Tabriz Univ Med Sci, Cardiovasc Res Ctr, Tabriz, Iran

[4] Tabriz Univ Med Sci, Fac Med, Dept Physiol, Tabriz, Iran

[5] Tabriz Univ Med Sci, Fac Med, Dept Microbiol, Tabriz, Iran

来源：

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES | 2018年 / 37卷 / 12期

关键词：

Viral infection; Atherosclerosis; Inflammation; HERPES-SIMPLEX-VIRUS; PARVOVIRUS B19 INFECTION; C-REACTIVE PROTEIN; HEPATITIS-B-VIRUS; CORONARY-ARTERY-DISEASE; NECROSIS-FACTOR-ALPHA; EPSTEIN-BARR-VIRUS; CARDIOVASCULAR-DISEASE; RISK-FACTOR; CYTOMEGALOVIRUS-INFECTION;

D O I：

10.1007/s10096-018-3370-z

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Several risk factors have been described for the pathogenesis of atherosclerosis. Infectious diseases are suggested to be a causative factor, and some viruses have been studied for their relation with atherosclerotic diseases. Studies report two hypotheses, direct and indirect effects, for the role of viral infections in atherogenesis. Viruses are able to initiate atherosclerosis by two different pathways. They can exert their direct effects on atherogenesis by infecting vascular cells and then inducing inflammation in the endothelium and smooth muscle cells. Alternatively, they can also apply indirect effects by infecting non-vascular cells and inducing systemic inflammation. In this review, we consider the available data about the effects and correlations of DNA and RNA viruses on atherosclerosis.

引用

页码：2225 / 2233

页数：9

共 91 条

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