Fluid-structure interaction analysis of the left coronary artery with variable angulation

被引:51
作者
Dong, Jingliang [1 ]
Sun, Zhonghua [2 ]
Inthavong, Kiao [1 ]
Tu, Jiyuan [1 ]
机构
[1] RMIT Univ, PTRI, Sch Aerosp Mech & Mfg Engn, Bundoora, Vic 3083, Australia
[2] Curtin Univ, Dept Imaging & Appl Phys, Discipline Med Imaging, Perth, WA 6845, Australia
基金
澳大利亚研究理事会;
关键词
wall shear stress; left coronary artery; tensile stress; arterial wall compliance; branch angulation; fluid-structure interaction; HEMODYNAMIC SHEAR-STRESS; CAROTID BIFURCATION; WALL SHEAR; BLOOD-FLOW; SIGNAL-TRANSDUCTION; MECHANICAL FORCES; MASS-TRANSFER; PLAQUE; ATHEROSCLEROSIS; ANGLE;
D O I
10.1080/10255842.2014.921682
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
The aim of this study is to elucidate the correlation between coronary artery branch angulation, local mechanical and haemodynamic forces at the vicinity of bifurcation. Using a coupled fluid-structure interaction (FSI) modelling approach, five idealized left coronary artery models with various angles ranging from 70 degrees to 110 degrees were developed to investigate the influence of branch angulations. In addition, one CT image-based model was reconstructed to further demonstrate the medical application potential of the proposed FSI coupling method. The results show that the angulation strongly alters its mechanical stress distribution, and the instantaneous wall shear stress distributions are substantially moderated by the arterial wall compliance. As high tensile stress is hypothesized to cause stenosis, the left circumflex side bifurcation shoulder is indicated to induce atherosclerotic changes with a high tendency for wide-angled models.
引用
收藏
页码:1500 / 1508
页数:9
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