Synthesis of New Pyrazoles via Cycloaddition Reactions of Nitrilimines with 2-Cyclopentenone Derivatives

被引：10
|
作者：
El-Samahy, Fatma A. [1 ]
机构：
[1] Natl Res Ctr, Div Ind Chem, Cairo, Egypt
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 2015年 / 52卷 / 02期
关键词：
HIGHLY POTENT; 1,3-DIPOLES; INHIBITORS; HETEROCYCLES; DPC423;
D O I：
10.1002/jhet.2077
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Compounds 1,3,6,6a-tetraphenyl-1,6a-dihydrocyclopenta[c]pyrazol-4(3aH)-ones (3), 1,3,3a,4-tetraphenyl-1,3a-dihydrocyclopenta[c]pyrazol-6-ols (4) and 6-hydroxy-1,3,6,6a-tetraphenyl-1,5,6,6a-tetrahydrocyclopenta[c]pyrazole-4(aH)-one (5) were synthesized by reaction of 3,4-diphenyl-4-hydroxy-2-cyclopentenone (2a) with nitrilimines, generated in situ by the action of triethylamine on the corresponding hydrazonyl chlorides 1.
引用
收藏
页码：597 / 602
页数：6
相关论文
共 50 条
  • [21] Synthesis of Isoxazole and 1,2,3-Triazole Isoindole Derivatives via Silver-and Copper-Catalyzed 1,3-Dipolar Cycloaddition Reactions
    Rammah, Mohamed Mehdi
    Gati, Wafa
    Mtiraoui, Hasan
    Rammah, Mohamed El Baker
    Ciamala, Kabula
    Knorr, Michael
    Rousselin, Yoann
    Kubicki, Marek M.
    MOLECULES, 2016, 21 (03):
  • [22] Synthesis of Dispiro [indoline-3,3′-pyrrolo [2,1-a]isoquinoline-1′,2"-thiazolo[3,2-a]pyrimidine] Derivatives via Cycloaddition Reactions
    Liu Qin
    Hu Xiaolian
    Li Xiaofang
    RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2022, 92 (09) : 1822 - 1826
  • [23] Synthesis of New 5-Oxazolones: Their Ring Opening Reactions to Obtain New Benzamide Derivatives
    Gunkara, Omer Tahir
    Guleli, Muge
    Cevikkalp, Senem Akkus
    Kaya, Kerem
    Ocal, Nuket
    CURRENT ORGANIC SYNTHESIS, 2017, 14 (02) : 283 - 290
  • [24] Cycloaddition of trifluoromethyl azafulvenium methides: synthesis of new trifluoromethylpyrrole-annulated derivatives
    Nunes, Claudio M.
    Silva, Manuela Ramos
    Beja, Ana Matos
    Fausto, Rui
    Pinho e Melo, Teresa M. V. D.
    TETRAHEDRON LETTERS, 2010, 51 (02) : 411 - 414
  • [25] Regioselective synthesis of novel dispiropyrrolidine and dispiropyrrolizidine oxindole derivatives via azomethine ylide specific [3+2]-cycloaddition
    Lanka, Srinu
    Thennarasu, Sathiah
    Perumal, Paramasivan T.
    RSC ADVANCES, 2014, 4 (05): : 2263 - 2266
  • [26] 1,3-Dipolar Cycloaddition of Carbodiimides and Nitrilimines: Synthesis and Mechanistic Study of 5-Amino-1,2,4-triazoles
    Yen, Wan-Ping
    Kung, Fung-Chun
    Wong, Fung Fuh
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2016, 2016 (13) : 2328 - 2335
  • [27] Catalyst-free three-component synthesis of new pyrrolidine derivatives via 1,3-dipolar cycloaddition
    Villarreal, Yazmin
    Insuasty, Braulio
    Abonia, Rodrigo
    Ortiz, Alejandro
    Quiroga, Jairo
    CHEMISTRY OF HETEROCYCLIC COMPOUNDS, 2019, 55 (4-5) : 352 - 358
  • [28] Synthesis of 1,2,3-Triazole-Fused Heterocycles via Intramolecular Azide-Alkyne Cycloaddition Reactions
    Majumdar, Krishna C.
    Ray, Krishanu
    SYNTHESIS-STUTTGART, 2011, (23): : 3767 - 3783
  • [29] Synthesis of 3,5-bis(fluoroalkyl)pyrazoles/pyrazolines via [3+2] cycloaddition of di/trifluoroacetohydrazonoyl bromides and trifluoromethyl-substituted alkenes
    Wang, Ruikang
    Jin, Peng
    Yang, Gaowang
    Fan, Ying
    Bai, Zuyu
    Huang, Danfeng
    Wang, Ke-Hu
    Wang, Junjiao
    Hu, Yulai
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2025, 23 (03) : 638 - 648
  • [30] Synthesis of 1,2,4-azadiphosphole derivatives based on vanadium-catalyzed [2+2+1] cycloaddition reactions of azobenzenes with phosphaalkynes
    Liang, Wenbin
    Nakajima, Kazunari
    Nishibayashi, Yoshiaki
    RSC ADVANCES, 2020, 10 (22) : 12730 - 12733
12345