Living with p53, dying of p53

被引:256
作者
Aylon, Yael [1 ]
Oren, Moshe [1 ]
机构
[1] Weizmann Inst Sci, Dept Mol Cell Biol, IL-76100 Rehovot, Israel
关键词
D O I
10.1016/j.cell.2007.08.005
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The p53 tumor suppressor protein acts as a major defense against cancer. Among its most distinctive features is the ability to elicit both apoptotic death and cell cycle arrest. In this issue of Cell, Das et al. ( 2007) and Tanaka et al. ( 2007) provide new insights into the mechanisms that dictate the life and death decisions of p53.
引用
收藏
页码:597 / 600
页数:4
相关论文
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