Quantification of Staphylococcus aureus using surface acoustic wave sensors

被引:17
作者
Xu, Zhangliang [1 ,2 ]
Yuan, Yong J. [1 ]
机构
[1] Southwest Jiaotong Univ, Sch Mat Sci & Engn, Lab Biosensing & MicroMechatron, Chengdu 610031, Sichuan, Peoples R China
[2] Chongqing Univ Sci & Technol, Sch Met & Mat Engn, Chongqing 401331, Peoples R China
基金
国家重点研发计划;
关键词
BOND RUPTURE; BACTERIA; FOOD; IDENTIFICATION; IMMUNOSENSOR; BIOSENSORS; DEVICE; MILK;
D O I
10.1039/c8ra09790a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Quartz crystal microbalance (QCM), surface acoustic wave (SAW)-Rayleigh and ZnO based SAW-Love sensors were fabricated and their sensitivity was comparatively analyzed for the quantification of Staphylococcus aureus (S. aureus). The SAW based sensors showed response magnitudes up to three times greater than that of the QCM sensor for the same mass loading of S. aureus. The ZnO nanoparticle-based SAW-Love sensor has a maximum mass loading sensitivity of 328.75 Hz ng(-1). The SAW-Love sensor achieved a lower limit of detection of 2 x 10(3) CFU mL(-1) compared to the QCM counterpart (2 x 10(5) to 2 x 10(6) CFU mL(-1)) under the same conditions. The SAW-Love sensor could be used as a disposable chip in micro or ultra-trace accurate diagnosis methods.
引用
收藏
页码:8411 / 8414
页数:4
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