Practical guidelines for physicians in the management of febrile seizures

被引:42
作者
Fukuyama, Y
Seki, T
Ohtsuka, C
Miura, H
Hara, M
机构
[1] KEIO UNIV,SCH MED,DEPT PEDIAT,TOKYO,JAPAN
[2] JUNTENDO UNIV,URAYASU HOSP,SCH MED,URAYASU,CHIBA,JAPAN
[3] KITASATO UNIV,SCH MED,DEPT PEDIAT,SAGAMIHARA,KANAGAWA 228,JAPAN
[4] GUNMA UNIV,FAC EDUC,DEPT SPECIAL EDUC HANDICAPPED,MAEBASHI,GUMMA 371,JAPAN
关键词
febrile seizure; diazepam suppository; intermittent therapy; physician's guideline; prophylaxis; risk factor; warning factor;
D O I
10.1016/S0387-7604(96)00066-6
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Recent studies have shown that adequate medication can prevent the recurrence of febrile seizures (FS). It has also been clarified that the vast majority of, though not all, FS patients follow a benign course. Then, questions arise as to whether or not FS should be prevented, particularly in light of the risks of side effects from drugs. Which kinds of FS can be prevented, if necessary? The guidelines presented here are aimed primarily at helping general practitioners in considering how to manage FS most appropriately. The guidelines stress that judgements should be individualized, while referring to a few specific 'warning factors'. The guidelines follow a 'laissez-faire' principle for the majority of FS cases, whereas intermittent therapy with diazepam and continuous medication with either phenobarbital or valproate are indicated in other limited cases meeting respective definite criteria.
引用
收藏
页码:479 / 484
页数:6
相关论文
共 14 条
[1]   FACTORS PROGNOSTIC OF UNPROVOKED SEIZURES AFTER FEBRILE CONVULSIONS [J].
ANNEGERS, JF ;
HAUSER, WA ;
SHIRTS, SB ;
KURLAND, LT .
NEW ENGLAND JOURNAL OF MEDICINE, 1987, 316 (09) :493-498
[2]   PREDICTORS OF RECURRENT FEBRILE SEIZURES - A META-ANALYTIC REVIEW [J].
BERG, AT ;
SHINNAR, S ;
HAUSER, WA ;
LEVENTHAL, JM .
JOURNAL OF PEDIATRICS, 1990, 116 (03) :329-337
[3]   FEBRILE SEIZURES AND LATER INTELLECTUAL-PERFORMANCE [J].
ELLENBERG, JH ;
NELSON, KB .
ARCHIVES OF NEUROLOGY, 1978, 35 (01) :17-21
[4]  
KAGAWA K, 1992, NEW MOOK PEDIAT SERI, V2, P23
[5]  
KNUDSEN FU, 1990, COMPREHENSIVE EPILEP, P133
[6]  
MATSUMOTO T, 1986, NIHON IJI SHINPO TOK, V3241, P43
[7]   PHARMACOKINETICS OF RECTAL DIAZEPAM IN THE PREVENTION OF RECURRENT FEBRILE CONVULSIONS [J].
MINAGAWA, K ;
MIURA, H ;
MIZUNO, S ;
SHIRAI, H .
BRAIN & DEVELOPMENT, 1986, 8 (01) :53-59
[8]  
MIURA H, 1992, NEW MOOK PEDIAT SERI, V2, P88
[9]   PREDICTORS OF EPILEPSY IN CHILDREN WHO HAVE EXPERIENCED FEBRILE SEIZURES [J].
NELSON, KB ;
ELLENBERG, JH .
NEW ENGLAND JOURNAL OF MEDICINE, 1976, 295 (19) :1029-1033
[10]  
OHTAHARA S, 1984, NO KENKYUKAI KAISHI, V6, P365