Molecular mechanisms in the regulation of renal proximal tubular Na/phosphate cotransport

被引：4
|
作者：
Murer, H [1 ]
Lotscher, M [1 ]
Kaissling, B [1 ]
Biber, J [1 ]
机构：
[1] INST ANAT,CH-8057 ZURICH,SWITZERLAND
来源：
KIDNEY & BLOOD PRESSURE RESEARCH | 1996年 / 19卷 / 3-4期
关键词：
brush border membrane; proximal tubule; phosphate reabsorption; parathyroid hormone; low-phosphate diet; X-linked hypophosphatemia;
D O I：
10.1159/000174063
中图分类号：
Q4 [生理学];
学科分类号：
071003 ;
摘要：
Renal proximal tubular Na/phosphate cotransport is the key target in the control of renal phosphate handling. Using molecular tools for the type II Na/phosphate cotransporter, it could be documented that altered brush border membrane phosphate transport reflects a state of altered brush border expression of the specific transporter molecule. This alteration is either the consequence of specific membrane insertion/retrieval processes and/or reflects states of altered synthesisdegradation of the transporter.
引用
收藏
页码：151 / 154
页数：4
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