Macro CK in patients with elevated troponin I levels

被引:2
作者
Kohli-Kochhar, Ruchika [1 ]
Mulwa, Evelyne [1 ]
Omuse, Geoffrey [1 ]
Ojwang, Peter [1 ]
机构
[1] Aga Khan Univ Hosp, Dept Pathol, Nairobi, Kenya
关键词
macro CK; CK-MB interference; elevated troponin I; CREATINE-KINASE TYPE-1; CLINICAL-SIGNIFICANCE; MACROENZYMES; PREVALENCE; SERUM; ISOENZYME;
D O I
10.5830/CVJA-2010-082
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
CK-MB activity levels can be falsely elevated by the presence of macro CK, especially if immuno-inhibition assays are used in the measurement. In patients with macro CK and cardiac pathology that could result in an elevated CK-MB activity, the diagnostic challenge lies in determining the true cause of the elevated CK-MB activity. We present two case reports of patients with elevated CK-MB activity and troponin I levels, but who subsequently had CK-MB activity higher than total CK activity, raising the suspicion of the presence of macro CK.
引用
收藏
页码:E7 / E10
页数:4
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