Allergy to neuromuscular blocking agents

被引：3

作者：

Chiriac, Anca-Mirela ^{[1
,2
]}

Demoly, Pascal ^{[1
,2
]}

机构：

[1] Ctr Hosp Univ Montpellier, Dept Pneumol & Addictol, Hop Arnaud de Villeneuve, Unite Explorat Allergies, F-34295 Montpellier, France

[2] UPMC Paris 06, Sorbonne Univ, Inst Pierre Louis Epidemiol & Sante Publ, UMR S 1136,Equipe EPAR, F-75013 Paris, France

来源：

PRESSE MEDICALE | 2016年 / 45卷 / 09期

关键词：

INDUCED ANAPHYLACTIC SHOCK; PREDICTIVE-VALUE; DRUG ALLERGY; SUGAMMADEX; ROCURONIUM; ANTIBODIES; ANESTHESIA; RECOVERY; TESTS;

D O I：

10.1016/j.lpm.2016.02.023

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Allergy to neuromuscular blocking agents (NMBAs) has been the first cause of perioperative anaphylaxis for decades, in most countries. The most frequently involved agents are suxamethonium and rocuronium. The allergy work-up is compulsory to demonstrate or rule out allergy to NMBAs, if there is a compatible clinical history. Doing otherwise exposes the patient to death if the same or related NMBA is re-injected. In cases of true allergy, assessing cross-reactivity to other NMBAs is mandatory. The cross-sensitization hypothesis is presently being investigated and if confirmed, it could allow primary prevention measures to be implemented.

引用

页码：768 / 773

页数：6

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