Splenectomy as a therapeutic approach in refractory hemophagocytic lymphohistiocytosis

被引：4
作者：
Machaczka, Maciej [1 ,2 ]
机构：
[1] Karolinska Inst, Div Hematol, Dept Med Huddinge, SE-14186 Stockholm, Sweden
[2] Karolinska Univ, Huddinge Hosp, Hematol Ctr Karolinska, SE-14186 Stockholm, Sweden
来源：
BIOMEDICINE & PHARMACOTHERAPY | 2012年 / 66卷 / 02期
关键词：
Hemophagocytic lymphohistiocytosis; Splenectomy; Therapy; MUTATIONS;
D O I：
10.1016/j.biopha.2011.09.009
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Zhang et al. have reported a case of an adult man with hemophagocytic lymphohistiocytosis (HLH) with an unknown etiology who has achieved a remission of HLH following comprehensive treatment based on splenectomy. In the present communication, the author critically discusses diagnostic and therapeutic issues related to the reported case, and questions utility of splenectomy in the treatment of active HLH.
引用
收藏
页码：159 / 160
页数：2
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