Plasma exchange versus intravenous immunoglobulin treatment in myasthenic crisis

被引：115

作者：

Qureshi, AI

Choudhry, MA

Akbar, MS

Mohammad, Y

Chua, HC

Yahia, AM

Ulatowski, JA

Krendel, DA

Leshner, RT

机构：

[1] Johns Hopkins Hosp, Dept Neurol, Baltimore, MD USA

[2] Virginia Commonwealth Univ, Med Coll Virginia, Dept Neurol, Richmond, VA 23298 USA

[3] Emory Univ, Sch Med, Dept Neurol, Atlanta, GA USA

[4] Med Coll Wisconsin, Dept Neurol, Milwaukee, WI 53226 USA

来源：

NEUROLOGY | 1999年 / 52卷 / 03期

关键词：

D O I：

10.1212/WNL.52.3.629

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We performed a retrospective multicenter chart review to compare the efficacy and tolerance of plasma exchange (PE) and intravenous immunoglobulin (IVIg) in treatment of 54 episodes of myasthenic crisis. After adjustment for other variables, PE (compared with Mg) was associated with a superior ventilatory status at 2 weeks (partial F = 6.2, p = 0.02) and 1 month functional outcome (partial F = 4.5, p = 0.04). However, the complication rate was higher with PE compared with IVIg (13 versus 5 episodes, p = 0.07).

引用

页码：629 / 632

页数：4

共 9 条

[1] ARSURA E, 1989, CLIN IMMUNOL IMMUNOP, V53, P170
[2] OPINIONS ABOUT PLASMA-EXCHANGE AND ASSOCIATED TREATMENTS IN THE THERAPY OF MYASTHENIA-GRAVIS
BERGAMINI, L
COCITO, D
DURELLI, L
QUATTROCOLO, G
[J]. MUSCLE & NERVE, 1983, 6 (06) : 457 - 458
[3] Therapy of myasthenic crisis
Berrouschot, J
Baumann, I
Kalischewski, P
Sterker, M
Schneider, D
[J]. CRITICAL CARE MEDICINE, 1997, 25 (07) : 1228 - 1235
[4] *CRUNCH SOFTW CORP, 1991, CRUNCH 4 0 STAT SOFT
[5] DEAN AG, 1995, EPI INFO 6 WORD PROC
[6] Clinical trial of plasma exchange and high-dose intravenous immunoglobulin in myasthenia gravis
Gajdos, P
Chevret, S
Clair, B
Tranchant, C
Chastang, C
[J]. ANNALS OF NEUROLOGY, 1997, 41 (06) : 789 - 796
[7] MYASTHENIC CRISIS - RESPONSE TO PLASMAPHERESIS FOLLOWING FAILURE OF INTRAVENOUS GAMMA-GLOBULIN
STRICKER, RB
KWIATKOWSKA, BJ
HABIS, JA
KIPROV, DD
[J]. ARCHIVES OF NEUROLOGY, 1993, 50 (08) : 837 - 840
[8] ACUTE-RENAL-FAILURE RESULTING FROM INTRAVENOUS IMMUNOGLOBULIN THERAPY
TAN, E
HAJINAZARIAN, M
BAY, W
NEFF, J
MENDELL, JR
[J]. ARCHIVES OF NEUROLOGY, 1993, 50 (02) : 137 - 139
[9] Myasthenic crisis: Clinical features, mortality, complications, and risk factors for prolonged intubation
Thomas, CE
Mayer, SA
Gungor, Y
Swarup, R
Webster, EA
Chang, I
Brannagan, TH
Fink, ME
Rowland, LP
[J]. NEUROLOGY, 1997, 48 (05) : 1253 - 1260

← 1 →