Selective hemi-portocaval shunt based on portal vein pressure for small-for-size graft in adult living donor liver transplantation

被引:124
作者
Yamada, T. [1 ]
Tanaka, K. [2 ]
Uryuhara, K. [2 ]
Ito, K. [3 ]
Takada, Y. [1 ]
Uemoto, S. [1 ]
机构
[1] Kyoto Univ, Dept Surg, Hepato Pancreato Biliary Surg & Transplantat, Kyoto 6068501, Japan
[2] Kobe City Gen Hosp, Dept Surg, Kobe, Hyogo, Japan
[3] Kobe City Gen Hosp, Dept Radiol, Kobe, Hyogo, Japan
关键词
left lobe graft; live donor transplantation; portal pressure; portosystemic shunt; small-for size graft; small-for-size syndrome;
D O I
10.1111/j.1600-6143.2007.02144.x
中图分类号
R61 [外科手术学];
学科分类号
摘要
We developed an algorithm of graft selection in which left lobe donation is considered primarily if the graft-to-recipient weight ratio (GRWR) is estimated to be greater than 0.6% in preoperative volumetry with utilization of a hemi-portocaval shunt (HPCS) based on portal vein pressure (PVP) more than 20 mmHg at the time of laparotomy. A total of 11 consecutive adult living donor liver transplantations with small-for-size graft according to our graft selection algorithm were performed between December 2005 and August 2007. Ten patients required HPCS using a vein graft all survived without small-for-size syndrome (SFSS) and shunt complications with a median follow-up of 296 days. One patient without HPCS died of chronic vascular rejection. In all cases, PVP were regulated successfully under 20 mmHg by HPCS. Graft volume reached in mean 84.3% of standard liver volume in right lobe grafts and mean 95.4% in left lobe grafts at 3 months after liver transplantation. Actuarial rate of shunt patency at 1, 3, 6 months and 1 year were 80%, 55%, 26% and 20%, respectively. Selective HPCS based on PVP is an effective procedure and results in excellent patient and graft survival with avoidance of SFSS in grafts greater than 0.6% of GRWR.
引用
收藏
页码:847 / 853
页数:7
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