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Selective hemi-portocaval shunt based on portal vein pressure for small-for-size graft in adult living donor liver transplantation
被引:123
作者:
Yamada, T.
[1
]
Tanaka, K.
[2
]
Uryuhara, K.
[2
]
Ito, K.
[3
]
Takada, Y.
[1
]
Uemoto, S.
[1
]
机构:
[1] Kyoto Univ, Dept Surg, Hepato Pancreato Biliary Surg & Transplantat, Kyoto 6068501, Japan
[2] Kobe City Gen Hosp, Dept Surg, Kobe, Hyogo, Japan
[3] Kobe City Gen Hosp, Dept Radiol, Kobe, Hyogo, Japan
关键词:
left lobe graft;
live donor transplantation;
portal pressure;
portosystemic shunt;
small-for size graft;
small-for-size syndrome;
D O I:
10.1111/j.1600-6143.2007.02144.x
中图分类号:
R61 [外科手术学];
学科分类号:
摘要:
We developed an algorithm of graft selection in which left lobe donation is considered primarily if the graft-to-recipient weight ratio (GRWR) is estimated to be greater than 0.6% in preoperative volumetry with utilization of a hemi-portocaval shunt (HPCS) based on portal vein pressure (PVP) more than 20 mmHg at the time of laparotomy. A total of 11 consecutive adult living donor liver transplantations with small-for-size graft according to our graft selection algorithm were performed between December 2005 and August 2007. Ten patients required HPCS using a vein graft all survived without small-for-size syndrome (SFSS) and shunt complications with a median follow-up of 296 days. One patient without HPCS died of chronic vascular rejection. In all cases, PVP were regulated successfully under 20 mmHg by HPCS. Graft volume reached in mean 84.3% of standard liver volume in right lobe grafts and mean 95.4% in left lobe grafts at 3 months after liver transplantation. Actuarial rate of shunt patency at 1, 3, 6 months and 1 year were 80%, 55%, 26% and 20%, respectively. Selective HPCS based on PVP is an effective procedure and results in excellent patient and graft survival with avoidance of SFSS in grafts greater than 0.6% of GRWR.
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页码:847 / 853
页数:7
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