AMPLIFIED EGFR DRIVES TUMORIGENESIS IN TP53 WILD TYPE GLIOBLASTOMA THROUGH INHIBITION OF p53 FUNCTION BY DNA-PK/p53 BINDING

被引:0
|
作者
Ding, Jie [1 ]
Li, Xiaolong [1 ]
Wasylishen, Amanda [1 ]
Gao, Feng [1 ]
Zhao, Yang [1 ]
Baggerly, Keith [1 ]
Lozano, Guillermina [1 ]
Koul, Dimpy [1 ]
Yung, W. K. Alfred [1 ]
机构
[1] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
CBIO-02
引用
收藏
页码:33 / 33
页数:1
相关论文
共 50 条
  • [41] TP53 variants in p53 signatures and the clonality of STICs in RRSO samples
    Akahane, Tomoko
    Masuda, Kenta
    Hirasawa, Akira
    Kobayashi, Yusuke
    Ueki, Arisa
    Kawaida, Miho
    Misu, Kumiko
    Nakamura, Kohei
    Nagai, Shimpei
    Chiyoda, Tatsuyuki
    Yamagami, Wataru
    Hayashi, Shigenori
    Kataoka, Fumio
    Banno, Kouji
    Sugano, Kokichi
    Okita, Hajime
    Kosaki, Kenjiro
    Nishihara, Hiroshi
    Aoki, Daisuke
    JOURNAL OF GYNECOLOGIC ONCOLOGY, 2022, 33 (04)
  • [42] A novel mutant p53 binding partner BAG5 stabilizes mutant p53 and promotes mutant p53 GOFs in tumorigenesis
    Xuetian Yue
    Yuhan Zhao
    Grace Huang
    Jun Li
    Junlan Zhu
    Zhaohui Feng
    Wenwei Hu
    Cell Discovery, 2
  • [43] Accumulation of p53 protein in pterygia is not accompanied by TP53 gene mutation
    Schneider, BG
    John-Aryankalayil, M
    Rowsey, JJ
    Dushku, N
    Reid, TW
    EXPERIMENTAL EYE RESEARCH, 2006, 82 (01) : 91 - 98
  • [44] A novel mutant p53 binding partner BAG5 stabilizes mutant p53 and promotes mutant p53 GOFs in tumorigenesis
    Yue, Xuetian
    Zhao, Yuhan
    Huang, Grace
    Li, Jun
    Zhu, Junlan
    Feng, Zhaohui
    Hu, Wenwei
    CELL DISCOVERY, 2016, 2
  • [45] Concordance of p53 Immunohistochemistry and TP53 Mutation Status in Endometrial Cancer
    Paula, Arnaud Da Cruz
    DeLair, Deborah
    Fix, Daniel
    Soslow, Robert
    Park, Kay
    Chiang, Sarah
    Reis-Filho, Jorge
    Zehir, Ahmet
    Murali, Rajmohan
    Makker, Vicky
    Cadoo, Karen
    Mueller, Jennifer
    Leitao, Mario
    Abu-Rustum, Nadeem
    Aghajanian, Carol
    Weigelt, Britta
    MODERN PATHOLOGY, 2020, 33 (SUPPL 2) : 1034 - 1035
  • [46] TP53 gene and p53 protein vs. endometrial carcinoma
    Zajac, Agnieszka
    Stachowiak, Grzegorz
    Stetkiewicz, Tomasz
    Wilczynski, Jacek R.
    MENOPAUSE REVIEW-PRZEGLAD MENOPAUZALNY, 2013, 12 (03): : 228 - 230
  • [47] Focus on the p53 gene and cancer:: Advances in TP53 mutation research
    Soussi, T
    HUMAN MUTATION, 2003, 21 (03) : 173 - 175
  • [48] ADP-ribosylation of wild-type p53 in vitro: Binding of p53 protein to specific p53 consensus sequence prevents its modification
    WesierskaGadek, J
    Schmid, G
    Cerni, C
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1996, 224 (01) : 96 - 102
  • [49] TUMOR SUPPRESSOR P53 - ANALYSIS OF WILD-TYPE AND MUTANT P53 COMPLEXES
    MILNER, J
    MEDCALF, EA
    COOK, AC
    MOLECULAR AND CELLULAR BIOLOGY, 1991, 11 (01) : 12 - 19
  • [50] Role of p53 in the inhibition of proliferation of gastric cancer cells expressing wild-type or mutated p53
    Ji, Wansheng
    Ma, Jingrong
    Zhang, Hongmei
    Zhong, Hua
    Li, Lei
    Ding, Na
    Jiao, Jianxin
    Gao, Zhixing
    MOLECULAR MEDICINE REPORTS, 2015, 12 (01) : 691 - 695