Two-photon Excitable Photosensitizers with Aggregation-induced Emission and Their Biomedical Applications

被引:12
作者
Wu, Wenbo [1 ]
Liu, Bin [1 ]
机构
[1] Natl Univ Singapore, Dept Chem & Biomol Engn, Singapore 117585, Singapore
来源
CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE | 2020年 / 41卷 / 02期
基金
新加坡国家研究基金会;
关键词
Aggregation-induced emission; Photosensitizer; Photodynamic therapy; Two-photon excitation; PHOTODYNAMIC THERAPY; NANOPARTICLES; MITOCHONDRIA; COMPLEXES; MECHANISMS; EXCITATION; AIEGENS; CELLS;
D O I
10.7503/cjcu20190614
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The concept of two-photon excited photodynamic therapy based on photosensitizers with aggregation-induced emission( AIE) takes advantages of high penetration depth and precision from two-photon technology , and high photosensitization efficiency in aggregate state from AIE photosensitizers. In this contribution, we review the recent progress in this field, which includes the design principles of two-photon excitable AIE photosensitizers , specific examples of AIE photosensitizers and their biomedical applications. The perspectives for the future development of this field was also discussed.
引用
收藏
页码:191 / 203
页数:13
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