Common causes of false positive F18FDG PET/CT scans in oncology

PET/CT is a common imaging modality used in the evaluation of oncology patients. While being extremely sensitive to identifying sights of malignancy F(18)FDG is very non-specific. We attempted to provide a brief review of some of the more common processes that a nuclear radiology physician may encounter in daily clinical practice that could result in a false positive diagnosis with F(18)FDG PET/CT. A fundamental understanding of the limitations of this technology by the interpreting physician is necessary to avoid making inaccurate diagnosis and potentially limiting important treatments for our patients.