miR-23a, a Critical Regulator of "migR" ation and Metastasis in Colorectal Cancer

被引：36
|
作者：
Wang, Zhiwei [2 ]
Wei, Wenyi [2 ]
Sarkar, Fazlul H. [1 ]
机构：
[1] Wayne State Univ, Karmanos Canc Inst, Dept Pathol & Oncol, Detroit, MI 48201 USA
[2] Harvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Dept Pathol, Boston, MA 02215 USA
来源：
CANCER DISCOVERY | 2012年 / 2卷 / 06期
关键词：
ONCOGENIC MICRORNA-27A; CELLS; SUPPRESSOR;
D O I：
10.1158/2159-8290.CD-12-0177
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Jahid and colleagues have shown that miR-23a promotes the transition from indolent to invasive colorectal cancer through inhibition of the MTSS1 tumor suppressor. This study reveals a novel role of miR-23a in the acceleration of colorectal cancer progression. Cancer Discov; 2(6); 489-91. (C) 2012 AACR.
引用
收藏
页码：489 / 491
页数：3
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