Metagenomics;
Big Data Technology;
High-Throughput Sequencing;
Bioinformatics Analysis;
16S RIBOSOMAL-RNA;
AMERICAN LIGHT SMOKERS;
MUSCA-DOMESTICA L;
INSENSITIVE ACETYLCHOLINESTERASE;
BOTULINUM NEUROTOXINS;
MINE TAILINGS;
HOUSE-FLY;
BACTERIA;
COMMUNITIES;
STRAIN;
D O I:
10.1166/jmihi.2018.2350
中图分类号:
Q [生物科学];
学科分类号:
07 ;
0710 ;
09 ;
摘要:
Development of high-throughput sequencing technologies to promote the application of big data bacterial and metagenomics research is most critical, and requires a mature set of computational methods. The analysis is carried out using an integrated bioinformatics and information technology platform. Bioinformatics applied to bacterial metagenomics research plays a vital role in sequencing technologies based on big data processing. It runs through the metagenomics data collection and storage, data processing and analysis phase, which forms the biggest bottlenecks of the metagenomics process. This paper describes and summarizes commonly used techniques in high-throughput metagenomic sequencing bioinformatics analysis platform that is used for the analysis of important information. Within the next few decades, sequencing costs will decline and an increase in depth of sequencing will further increase metagenomics research in terms of data storage, data processing, and data mining complexity. Therefore, the techniques and methods pertaining to bioinformatics research are imperative. In the near future, we need to strengthen our basic analysis and storage platform to facilitate the analysis of the common bacteria, and resolve the bottlenecks of bioinformatics analysis. For this, critical breakthroughs need to be gradually developed. The methods described in this paper give a good insight into the big data technology revolving metagenomics research.
机构:
Chinese Acad Agr Sci, Tobacco Res Inst, Qingdao, Peoples R China
Chinese Acad Agr Sci, Grad Sch, Beijing, Peoples R ChinaChinese Acad Agr Sci, Tobacco Res Inst, Qingdao, Peoples R China
Gao, Yumeng
Wang, Yihui
论文数: 0引用数: 0
h-index: 0
机构:
Shandong China Tobacco Ind Ltd Co, Jinan, Peoples R ChinaChinese Acad Agr Sci, Tobacco Res Inst, Qingdao, Peoples R China
Wang, Yihui
Hou, Bingqing
论文数: 0引用数: 0
h-index: 0
机构:
Shandong China Tobacco Ind Ltd Co, Jinan, Peoples R ChinaChinese Acad Agr Sci, Tobacco Res Inst, Qingdao, Peoples R China
Hou, Bingqing
Zhang, Guo
论文数: 0引用数: 0
h-index: 0
机构:
Anhui Wannan Tobacco Ltd Co, Xuancheng, Peoples R ChinaChinese Acad Agr Sci, Tobacco Res Inst, Qingdao, Peoples R China
Zhang, Guo
Jiang, Chun
论文数: 0引用数: 0
h-index: 0
机构:
Anhui Wannan Tobacco Ltd Co, Xuancheng, Peoples R ChinaChinese Acad Agr Sci, Tobacco Res Inst, Qingdao, Peoples R China
Jiang, Chun
Fang, Song
论文数: 0引用数: 0
h-index: 0
机构:
Chinese Acad Agr Sci, Tobacco Res Inst, Qingdao, Peoples R ChinaChinese Acad Agr Sci, Tobacco Res Inst, Qingdao, Peoples R China
Fang, Song
Wang, Qian
论文数: 0引用数: 0
h-index: 0
机构:
Chinese Acad Agr Sci, Tobacco Res Inst, Qingdao, Peoples R ChinaChinese Acad Agr Sci, Tobacco Res Inst, Qingdao, Peoples R China
Wang, Qian
Ning, Yang
论文数: 0引用数: 0
h-index: 0
机构:
Chinese Acad Agr Sci, Tobacco Res Inst, Qingdao, Peoples R ChinaChinese Acad Agr Sci, Tobacco Res Inst, Qingdao, Peoples R China
机构:
Guangxi Univ Chinese Med, Basic Med Coll, Nanning, Peoples R ChinaGuangxi Univ Chinese Med, Basic Med Coll, Nanning, Peoples R China
Xu, Lijing
Cheng, Jinlai
论文数: 0引用数: 0
h-index: 0
机构:
China Acad Chinese Med Sci, Inst Chinese Mat Med, Beijing, Peoples R ChinaGuangxi Univ Chinese Med, Basic Med Coll, Nanning, Peoples R China
Cheng, Jinlai
Li, Zhuoxian
论文数: 0引用数: 0
h-index: 0
机构:
Guangxi Univ Chinese Med, Basic Med Coll, Nanning, Peoples R ChinaGuangxi Univ Chinese Med, Basic Med Coll, Nanning, Peoples R China
Li, Zhuoxian
Wen, Xiaoyu
论文数: 0引用数: 0
h-index: 0
机构:
Guilin Life & Hlth Career Tech Coll, Rehabil Coll, Guilin, Peoples R ChinaGuangxi Univ Chinese Med, Basic Med Coll, Nanning, Peoples R China
Wen, Xiaoyu
Sun, Yuhao
论文数: 0引用数: 0
h-index: 0
机构:
Univ Gottingen, Inst Microbiol & Genet, Dept Mol Genet, Gottingen, GermanyGuangxi Univ Chinese Med, Basic Med Coll, Nanning, Peoples R China
Sun, Yuhao
Xia, Meng
论文数: 0引用数: 0
h-index: 0
机构:
Guangxi Univ Chinese Med, Basic Med Coll, Nanning, Peoples R ChinaGuangxi Univ Chinese Med, Basic Med Coll, Nanning, Peoples R China
Xia, Meng
Leng, Jing
论文数: 0引用数: 0
h-index: 0
机构:
Guangxi Univ Chinese Med, Basic Med Coll, Nanning, Peoples R China
Guangxi Univ Chinese Med, Guangxi Key Lab Translat Med Treating High Inciden, Nanning, Peoples R ChinaGuangxi Univ Chinese Med, Basic Med Coll, Nanning, Peoples R China
机构:
State Key Laboratory of Efficient Production of Forest Resources, Beijing Key Laboratory of Forest Processing and Safety, College of Biological Sciences and Technology, Beijing Forestry University, BeijingState Key Laboratory of Efficient Production of Forest Resources, Beijing Key Laboratory of Forest Processing and Safety, College of Biological Sciences and Technology, Beijing Forestry University, Beijing
Fang Y.
Su G.
论文数: 0引用数: 0
h-index: 0
机构:
State Key Laboratory of Tree Genetics and Breeding, Key Laboratory of Silviculture of the State Forestry and Grassland Administration, Research Institute of Forestry, Chinese Academy of Forestry, BeijingState Key Laboratory of Efficient Production of Forest Resources, Beijing Key Laboratory of Forest Processing and Safety, College of Biological Sciences and Technology, Beijing Forestry University, Beijing
Su G.
Wang W.
论文数: 0引用数: 0
h-index: 0
机构:
College of Life Sciences, Northeast Forestry University, HarbinState Key Laboratory of Efficient Production of Forest Resources, Beijing Key Laboratory of Forest Processing and Safety, College of Biological Sciences and Technology, Beijing Forestry University, Beijing
Wang W.
Bai Y.
论文数: 0引用数: 0
h-index: 0
机构:
State Key Laboratory of Tree Genetics and Breeding, Key Laboratory of Silviculture of the State Forestry and Grassland Administration, Research Institute of Forestry, Chinese Academy of Forestry, BeijingState Key Laboratory of Efficient Production of Forest Resources, Beijing Key Laboratory of Forest Processing and Safety, College of Biological Sciences and Technology, Beijing Forestry University, Beijing
Bai Y.
Wang F.
论文数: 0引用数: 0
h-index: 0
机构:
State Key Laboratory of Efficient Production of Forest Resources, Beijing Key Laboratory of Forest Processing and Safety, College of Biological Sciences and Technology, Beijing Forestry University, BeijingState Key Laboratory of Efficient Production of Forest Resources, Beijing Key Laboratory of Forest Processing and Safety, College of Biological Sciences and Technology, Beijing Forestry University, Beijing
Wang F.
Pei D.
论文数: 0引用数: 0
h-index: 0
机构:
State Key Laboratory of Tree Genetics and Breeding, Key Laboratory of Silviculture of the State Forestry and Grassland Administration, Research Institute of Forestry, Chinese Academy of Forestry, BeijingState Key Laboratory of Efficient Production of Forest Resources, Beijing Key Laboratory of Forest Processing and Safety, College of Biological Sciences and Technology, Beijing Forestry University, Beijing
机构:
Ocean Univ Qingdao, Coll Fisheries, Qingdao 266003, Peoples R ChinaOcean Univ Qingdao, Coll Fisheries, Qingdao 266003, Peoples R China
Song Chenyu
Feng Ziyi
论文数: 0引用数: 0
h-index: 0
机构:
Ocean Univ Qingdao, Coll Fisheries, Qingdao 266003, Peoples R ChinaOcean Univ Qingdao, Coll Fisheries, Qingdao 266003, Peoples R China
Feng Ziyi
Li Chunhou
论文数: 0引用数: 0
h-index: 0
机构:
Chinese Acad Fishery Sci, South China Sea Fisheries Res Inst, Guangzhou 510300, Guangdong, Peoples R ChinaOcean Univ Qingdao, Coll Fisheries, Qingdao 266003, Peoples R China
Li Chunhou
Sun Zhicheng
论文数: 0引用数: 0
h-index: 0
机构:
Ocean Univ Qingdao, Coll Fisheries, Qingdao 266003, Peoples R ChinaOcean Univ Qingdao, Coll Fisheries, Qingdao 266003, Peoples R China
Sun Zhicheng
Gao Tianxiang
论文数: 0引用数: 0
h-index: 0
机构:
Zhejiang Ocean Univ, Natl Engn Res Ctr Marine Aquaculture, Zhoushan 316022, Peoples R ChinaOcean Univ Qingdao, Coll Fisheries, Qingdao 266003, Peoples R China
Gao Tianxiang
Song Na
论文数: 0引用数: 0
h-index: 0
机构:
Ocean Univ Qingdao, Coll Fisheries, Qingdao 266003, Peoples R ChinaOcean Univ Qingdao, Coll Fisheries, Qingdao 266003, Peoples R China
Song Na
Liu Lu
论文数: 0引用数: 0
h-index: 0
机构:
Ocean Univ Qingdao, Coll Fisheries, Qingdao 266003, Peoples R ChinaOcean Univ Qingdao, Coll Fisheries, Qingdao 266003, Peoples R China
机构:
Hunan Univ, Sch Elect & Informat Engn, Changsha 410012, Hunan, Peoples R ChinaHunan Univ Technol, Hunan Key Lab Biomed Nanomat & Devices, Zhuzhou 412007, Hunan, Peoples R China
Lu, Yutong
Chow, Franklin Wang-Ngai
论文数: 0引用数: 0
h-index: 0
机构:
Hong Kong Polytech Univ, Dept Hlth Technol & Informat, Hong Kong 999077, Peoples R ChinaHunan Univ Technol, Hunan Key Lab Biomed Nanomat & Devices, Zhuzhou 412007, Hunan, Peoples R China
Chow, Franklin Wang-Ngai
Leung, Polly Hang-Mei
论文数: 0引用数: 0
h-index: 0
机构:
Hong Kong Polytech Univ, Dept Hlth Technol & Informat, Hong Kong 999077, Peoples R ChinaHunan Univ Technol, Hunan Key Lab Biomed Nanomat & Devices, Zhuzhou 412007, Hunan, Peoples R China