The role of radiotherapy in adult soft tissues sarcoma of the extremities

被引：9

作者：

Cammelli, Silvia ^{[1
,2
]}

Cortesi, Annalisa ^{[3
]}

Buwenge, Milly ^{[1
,2
]}

Zamagni, Alice ^{[1
,2
]}

Ferioli, Martina ^{[1
,2
]}

Ghigi, Giulia ^{[3
]}

Romeo, Antonino ^{[3
]}

Morganti, Alessio G. ^{[1
,2
]}

机构：

[1] Univ Bologna, Radiat Oncol, IRCCS Azienda Osped, Bologna, Italy

[2] Alma Mater Studiorum Univ Bologna, Dept Expt Diagnost & Specialty Med DIMES, Bologna, Italy

[3] IRCCS Ist Romagnolo Studio Tumori IRST Dino Amado, Radiotherapy Unit, Meldola, Italy

来源：

EUROPEAN JOURNAL OF ORTHOPAEDIC SURGERY AND TRAUMATOLOGY | 2021年 / 31卷 / 08期

关键词：

Soft tissue sarcoma; Radiotherapy; Extremities; Limbs; Review; MODULATED RADIATION-THERAPY; LIMB-SPARING SURGERY; POSTOPERATIVE RADIOTHERAPY; NEOADJUVANT CHEMOTHERAPY; LUNG METASTASES; HIGH-RISK; PREOPERATIVE RADIOTHERAPY; AMERICAN BRACHYTHERAPY; ADJUVANT CHEMOTHERAPY; CONSENSUS STATEMENT;

D O I：

10.1007/s00590-021-02990-6

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

Local management of adult soft tissue sarcoma of the extremities has evolved over the past decades. Until the 1970s, radical surgery (amputations) was the standard therapeutic procedure resulting in significant physical and psychological morbidity for the patients. In the present era, limb sparing surgery combined with radiotherapy represents the current standard of care for high grade and>5 cm STSs. This approach guarantees high local control rate and function preservation. The aim of this paper is to summarize the current evidence for RT in STSs of the extremities. Outcomes, technical details (techniques, timing, dose, volumes of treatment) and the emerging role of RT in the management of oligometastatic disease will be analysed. Finally, results of the recent clinical trials testing new scenarios in RT of STSs will be described.

引用

页码：1583 / 1596

页数：14

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