Approaches for Head and Neck Cancer Research - Current Status and the Way Forward

被引:1
|
作者
Barghavi, V. [1 ]
Femina, T. Arokia [1 ]
Iyengar, DivyaSowrirajan [1 ]
Archana, K. [1 ]
Ravi, Maddaly [1 ]
机构
[1] Sri Ramachandra Inst Higher Educ & Res, Fac Biomed Sci, Dept Human Genet, Chennai 600116, Tamil Nadu, India
关键词
Cell lines; 3D aggregates; xenografts; organoids; precision medicine; SQUAMOUS-CELL CARCINOMA; RISK HUMAN-PAPILLOMAVIRUS; IN-VITRO; INDUCED APOPTOSIS; DRUG-SENSITIVITY; GENE-EXPRESSION; TUMOR-GROWTH; LINE; MODEL; INVASION;
D O I
10.1080/07357907.2021.2009850
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Head and neck cancers (HNCs) are seeing an increasing trend in their prevalence among both genders and are the seventh most common cancer type occurring at the global level. Studies addressing both the cancer cell physiology and individual differences in response to a specific treatment modality should be understood for arriving at effective treatment and management of the HNCs. In this article, we discuss the trends in HNC research and their various approaches starting from 2D in vitro models, which are the traditional experimental materials to recently established Cancer-Tissue Originated Spheroids (CTOS) distinctly contributing towards personalized or precision medicine.
引用
收藏
页码:151 / 172
页数:22
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