Approaches for Head and Neck Cancer Research - Current Status and the Way Forward

被引：1
作者：
Barghavi, V. [1 ]
Femina, T. Arokia [1 ]
Iyengar, DivyaSowrirajan [1 ]
Archana, K. [1 ]
Ravi, Maddaly [1 ]
机构：
[1] Sri Ramachandra Inst Higher Educ & Res, Fac Biomed Sci, Dept Human Genet, Chennai 600116, Tamil Nadu, India
来源：
CANCER INVESTIGATION | 2022年 / 40卷 / 02期
关键词：
Cell lines; 3D aggregates; xenografts; organoids; precision medicine; SQUAMOUS-CELL CARCINOMA; RISK HUMAN-PAPILLOMAVIRUS; IN-VITRO; ANTITUMOR-ACTIVITY; INDUCED APOPTOSIS; DRUG-SENSITIVITY; GENE-EXPRESSION; TUMOR-GROWTH; LINE; MODEL;
D O I：
10.1080/07357907.2021.2009850
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Head and neck cancers (HNCs) are seeing an increasing trend in their prevalence among both genders and are the seventh most common cancer type occurring at the global level. Studies addressing both the cancer cell physiology and individual differences in response to a specific treatment modality should be understood for arriving at effective treatment and management of the HNCs. In this article, we discuss the trends in HNC research and their various approaches starting from 2D in vitro models, which are the traditional experimental materials to recently established Cancer-Tissue Originated Spheroids (CTOS) distinctly contributing towards personalized or precision medicine.
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收藏
页码：151 / 172
页数：22
相关论文
共 145 条
[1]   In vitro humanized 3D microfluidic chip for testing personalized immunotherapeutics for head and neck cancer patients [J].
Al-Samadi, Ahmed ;
Poor, Benedek ;
Tuomainen, Katja ;
Liu, Ville ;
Hyytiainen, Aini ;
Suleymanova, Ilida ;
Mesimaki, Karri ;
Wilkman, Tommy ;
Makitie, Antti ;
Saavalainen, Paivi ;
Salo, Tuula .
EXPERIMENTAL CELL RESEARCH, 2019, 383 (02)
[2]  
[Anonymous], 2002, Demogr Res
[3]   Retinoblastoma RB94 enhances radiation treatment of head and neck squamous cell carcinoma [J].
Araki, Koji ;
Ahmad, Sidrah M. ;
Li, Guoyan ;
Bray, David A., Jr. ;
Saito, Koichiro ;
Wang, Daiyou ;
Wirtz, Uwe ;
Sreedharan, Sunil ;
O'Malley, Bert W., Jr. ;
Li, Daqing .
CLINICAL CANCER RESEARCH, 2008, 14 (11) :3514-3519
[4]   In vitro study on anti-cancer properties of genistein in tongue cancer [J].
Ardito, Fatima ;
Pellegrino, Mario R. ;
Perrone, Donatella ;
Troiano, Giuseppe ;
Cocco, Armando ;
Lo Muzio, Lorenzo .
ONCOTARGETS AND THERAPY, 2017, 10 :5405-5415
[5]   Dissecting multi drug resistance in head and neck cancer cells using multicellular tumor spheroids [J].
Azharuddin, Mohammad ;
Roberg, Karin ;
Dhara, Ashis Kumar ;
Jain, Mayur Vilas ;
Darcy, Padraig ;
Hinkula, Jorma ;
Slater, Nigel K. H. ;
Patra, Hirak K. .
SCIENTIFIC REPORTS, 2019, 9 (1)
[6]   RETRACTED: The role of NF-κB and miRNA in oral cancer and cancer stem cells with or without HPV16 infection (Retracted Article) [J].
Bano, Nasreen ;
Yadav, Manisha ;
Mohania, Dheeraj ;
Das, Bhudev C. .
PLOS ONE, 2018, 13 (10)
[7]   Hypoxia modulates CCR7 expression in head and neck cancers [J].
Basheer, Haneen A. ;
Pakanavicius, Edvinas ;
Cooper, Patricia A. ;
Shnyder, Steven D. ;
Martin, Lisette ;
Hunter, Keith D. ;
Vinader, Victoria ;
Afarinkia, Kamyar .
ORAL ONCOLOGY, 2018, 80 :64-73
[8]  
Basuony Shaimaa Ali Hamouda Ali El, 2020, Braz. Dent. J., V31, P634, DOI 10.1590/0103-6440202003350
[9]   Establishment and Molecular Cytogenetic Characterization of a Cell Culture Model of Head and Neck Squamous Cell Carcinoma (HNSCC) [J].
Bauer, Verena L. ;
Hieber, Ludwig ;
Schaeffner, Quirin ;
Weber, Johannes ;
Braselmann, Herbert ;
Huber, Reinhard ;
Walch, Axel ;
Zitzelsberger, Horst .
GENES, 2010, 1 (03) :388-412
[10]  
Berndt A, 1997, INVAS METAST, V17, P251
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