Life expectancy of HIV-positive adults: a review

被引:70
作者
May, Margaret T. [1 ]
Ingle, Suzanne M. [1 ]
机构
[1] Univ Bristol, Sch Social & Community Med, Bristol BS8 2PS, Avon, England
基金
英国医学研究理事会;
关键词
aging; antiretroviral therapy; CD4; immunosuppression; prognosis; sociodemographics; COMBINATION ANTIRETROVIRAL THERAPY; HIGH-INCOME COUNTRIES; HIV-1-INFECTED PATIENTS; COLLABORATIVE ANALYSIS; IMPROVED SURVIVAL; INFECTED PATIENTS; GENERAL-POPULATION; VIRAL SUPPRESSION; SAN-FRANCISCO; UNITED-STATES;
D O I
10.1071/SH11046
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
We review studies estimating life expectancy (LE), the average number of additional years a person can expect to live, for HIV-positive adults and show variation by sociodemographic factors and level of immunosuppression. The LE of patients starting antiretroviral therapy early in the course of HIV infection and attaining restoration of a normal CD4 count may approach that of the general population. Improvements in treatment and the associated increase in LE imply that increasing numbers of HIV-positive patients will live to older age. Late diagnosis and presentation to care and treatment not concordant with guidelines contribute to reducing LE.
引用
收藏
页码:526 / 533
页数:8
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