Monitoring p53's pulse

被引:30
|
作者
Tyson, JJ [1 ]
机构
[1] Virginia Polytech Inst & State Univ, Blacksburg, VA 24061 USA
关键词
D O I
10.1038/ng0204-113
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
The tumor-suppressor protein p53 mediates the response of mammalian cells to DNA damage. Studies now show that DNA damage elicits quantal pulses of p53, with greater damage eliciting more pulses.
引用
收藏
页码:113 / 114
页数:2
相关论文
共 50 条
  • [1] Monitoring p53's pulse
    John J Tyson
    Nature Genetics, 2004, 36 : 113 - 114
  • [2] p53, a protein with a pulse
    Casci, T
    NATURE REVIEWS GENETICS, 2004, 5 (03) : 162 - 163
  • [3] p53, a protein with a pulse
    Tanita Casci
    Nature Reviews Genetics, 2004, 5 : 162 - 162
  • [4] p53's Extended Reach: The Mutant p53 Secretome
    Pavlakis, Evangelos
    Stiewe, Thorsten
    BIOMOLECULES, 2020, 10 (02)
  • [5] Exploring the mechanism of the excitability of p53 pulse response
    Ma, Aiqing
    Dai, Xianhua
    2018 INTERNATIONAL CONFERENCE ON COMPUTER INFORMATION SCIENCE AND APPLICATION TECHNOLOGY, 2019, 1168
  • [6] Living with p53, dying of p53
    Aylon, Yael
    Oren, Moshe
    CELL, 2007, 130 (04) : 597 - 600
  • [7] p53 in Hodgkin's disease
    Naranjo, TA
    Usach, MTS
    Princep, RB
    Gonzalez, SM
    MEDICINA CLINICA, 1996, 106 (10): : 398 - 399
  • [8] p53, the genome's guardian
    Perrier, JJ
    RECHERCHE, 1996, (283): : 31 - 32
  • [9] What's new in p53
    Maritsi, D.
    Stagikas, D.
    Charalabopoulos, K.
    Batistatou, A.
    HIPPOKRATIA, 2006, 10 (03) : 116 - 119
  • [10] p53's place in the sun
    不详
    NATURE MEDICINE, 2007, 13 (04) : 416 - 416