Indispensable tools: embryonic stem cells yield insights into the human heart

被引：10
作者：
Hescheler, J [1 ]
Fleischmann, BK [1 ]
机构：
[1] Univ Cologne, Inst Neurophysiol, D-50931 Cologne, Germany
来源：
JOURNAL OF CLINICAL INVESTIGATION | 2001年 / 108卷 / 03期
关键词：
D O I：
10.1172/JCI200113634
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
引用
收藏
页码：363 / 364
页数：2
相关论文
共 12 条
[1]   Embryonic stem cells: a model to study structural and functional properties in cardiomyogenesis [J].
Hescheler, J ;
Fleischmann, BK ;
Lentini, S ;
Maltsev, VA ;
Rohwedel, J ;
Wobus, AM ;
Addicks, K .
CARDIOVASCULAR RESEARCH, 1997, 36 (02) :149-162
[2]   Establishment of ionic channels and signalling cascades in the embryonic stem cell-derived primitive endoderm and cardiovascular system [J].
Hescheler, J ;
Fleischmann, BK ;
Wartenberg, M ;
Bloch, W ;
Kolossov, E ;
Ji, G ;
Addicks, K ;
Sauer, H .
CELLS TISSUES ORGANS, 1999, 165 (3-4) :153-164
[3]   Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes [J].
Kehat, I ;
Kenyagin-Karsenti, D ;
Snir, M ;
Segev, H ;
Amit, M ;
Gepstein, A ;
Livne, E ;
Binah, O ;
Itskovitz-Eldor, J ;
Gepstein, L .
JOURNAL OF CLINICAL INVESTIGATION, 2001, 108 (03) :407-414
[4]   Genetically selected cardiomyocytes from differentiating embryonic stem cells form stable intracardiac grafts [J].
Klug, MG ;
Soonpaa, MH ;
Koh, GY ;
Field, LJ .
JOURNAL OF CLINICAL INVESTIGATION, 1996, 98 (01) :216-224
[5]   STABLE FETAL CARDIOMYOCYTE GRAFTS IN THE HEARTS OF DYSTROPHIC MICE AND DOGS [J].
KOH, GY ;
SOONPAA, MH ;
KLUG, MG ;
PRIDE, HP ;
COOPER, BJ ;
ZIPES, DP ;
FIELD, LJ .
JOURNAL OF CLINICAL INVESTIGATION, 1995, 96 (04) :2034-2042
[6]  
Li RK, 1997, CIRCULATION, V96, P179
[7]   CARDIOMYOCYTES DIFFERENTIATED IN-VITRO FROM EMBRYONIC STEM-CELLS DEVELOPMENTALLY EXPRESS CARDIAC-SPECIFIC GENES AND IONIC CURRENTS [J].
MALTSEV, VA ;
WOBUS, AM ;
ROHWEDEL, J ;
BADER, M ;
HESCHELER, J .
CIRCULATION RESEARCH, 1994, 75 (02) :233-244
[8]   Survival, integration, and differentiation of cardiomyocyte grafts - A study in normal and injured rat hearts [J].
Reinecke, H ;
Zhang, M ;
Bartosek, T ;
Murry, CE .
CIRCULATION, 1999, 100 (02) :193-202
[9]  
ROELL W, 2001, PFLUGERS ARCH, V441, P153
[10]   Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells [J].
Schuldiner, M ;
Yanuka, O ;
Itskovitz-Eldor, J ;
Melton, DA ;
Benvenisty, N .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (21) :11307-11312
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