A convenient new synthesis of 1,2-diarylpyrroles from 3-ethoxycarbonyl-4-oxo-4-phenylbutyraldehyde

被引：0

作者：

Delayen, A ^{[1
]}

Goossens, L ^{[1
]}

Houssin, R ^{[1
]}

Hénichart, JP ^{[1
]}

机构：

[1] Univ Lille 2, Inst Chim Pharmaceut, F-59006 Lille, France

来源：

HETEROCYCLES | 2005年 / 65卷 / 07期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient four-step synthesis of ethyl 1,2-diaryl-3--pyrrole carboxylates (4), an isomeric scaffold of pharmacologically active natural products, is reported. The key synthon 3-ethoxycarbonyl-4-oxo-4-phenylbutyraldehyde (3), whose new synthesis is detailed here, reacts conveniently with anilines to create the pyrrole ring.

引用

页码：1673 / 1678

页数：6

共 28 条

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