Cobalt-Phenanthroline Catalysts for the ortho Alkylation of Aromatic Imines under Mild Reaction Conditions

被引：99

作者：

Gao, Ke ^{[1
]}

Yoshikai, Naohiko ^{[1
]}

机构：

[1] Nanyang Technol Univ, Div Chem & Biol Chem, Sch Phys & Math Sci, Singapore 637371, Singapore

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2011年 / 50卷 / 30期

基金：

新加坡国家研究基金会;

关键词：

alkenes; alkylation; C-H activation; cobalt; imines; C-H BOND; CARBON-HYDROGEN BONDS; CROSS-COUPLING REACTIONS; REGIOSELECTIVE ALKYLATION; RUTHENIUM CATALYST; TERMINAL ALKENES; RHODIUM CATALYST; ACTIVATION; OLEFINS; COMPLEXES;

D O I：

10.1002/anie.201101823

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Mild mannered: Cobalt catalysts complexed with phenanthroline-type ligands and activated with Grignard reagents serve as inexpensive and effective catalysts for the ortho alkylation of aromatic imines with a variety of olefins (see scheme). The new catalytic systems feature remarkably mild reaction conditions for C-H bond activation and functionalization. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：6888 / 6892

页数：5

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