Cobalt-Phenanthroline Catalysts for the ortho Alkylation of Aromatic Imines under Mild Reaction Conditions

被引：98
作者：
Gao, Ke [1 ]
Yoshikai, Naohiko [1 ]
机构：
[1] Nanyang Technol Univ, Div Chem & Biol Chem, Sch Phys & Math Sci, Singapore 637371, Singapore
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2011年 / 50卷 / 30期
基金：
新加坡国家研究基金会;
关键词：
alkenes; alkylation; C-H activation; cobalt; imines; C-H BOND; CARBON-HYDROGEN BONDS; CROSS-COUPLING REACTIONS; REGIOSELECTIVE ALKYLATION; RUTHENIUM CATALYST; TERMINAL ALKENES; RHODIUM CATALYST; ACTIVATION; OLEFINS; COMPLEXES;
D O I：
10.1002/anie.201101823
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Mild mannered: Cobalt catalysts complexed with phenanthroline-type ligands and activated with Grignard reagents serve as inexpensive and effective catalysts for the ortho alkylation of aromatic imines with a variety of olefins (see scheme). The new catalytic systems feature remarkably mild reaction conditions for C-H bond activation and functionalization. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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收藏
页码：6888 / 6892
页数：5
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