Effectiveness of terbinafine in the eradication of Microsporum canis from laboratory cats

被引：19

作者：

Castañón-Olivares, LR ^{[1
]}

Manzano-Gayosso, P ^{[1
]}

López-Martínez, R ^{[1
]}

De la Rosa-Velázquez, IA ^{[1
]}

Soto-Reyes-Solís, E ^{[1
]}

机构：

[1] Univ Nacl Autonoma Mexico, Fac Med, Dept Microbiol & Parasitol, Lab Micol Med, Mexico City 04510, DF, Mexico

来源：

MYCOSES | 2001年 / 44卷 / 3-4期

关键词：

Microsporum canis; cats; laboratory animals; terbinafine;

D O I：

10.1046/j.1439-0507.2001.00626.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

In this study, the coats of 20 cats with no dermatophytosis lesions were sampled for colonization by Microsporum canis, which was isolated in 45% of cases. All cats were treated with oral terbinafine for 3 weeks. The drug was administered orally at a daily dosage 8.25 mg kg (-1). Mycologic status was assessed at the end of the treatment; and after follow-up at 2 days, and 4 and 9 weeks. The final evaluation revealed a complete mycologic cure of all cats by obtaining negative cultures, thereby demonstrating that terbinafine is an effective method of eradication of dermatophyte colonization.

引用

页码：95 / 97

页数：3

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