Effectiveness of terbinafine in the eradication of Microsporum canis from laboratory cats

被引:18
作者
Castañón-Olivares, LR [1 ]
Manzano-Gayosso, P [1 ]
López-Martínez, R [1 ]
De la Rosa-Velázquez, IA [1 ]
Soto-Reyes-Solís, E [1 ]
机构
[1] Univ Nacl Autonoma Mexico, Fac Med, Dept Microbiol & Parasitol, Lab Micol Med, Mexico City 04510, DF, Mexico
关键词
Microsporum canis; cats; laboratory animals; terbinafine;
D O I
10.1046/j.1439-0507.2001.00626.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
In this study, the coats of 20 cats with no dermatophytosis lesions were sampled for colonization by Microsporum canis, which was isolated in 45% of cases. All cats were treated with oral terbinafine for 3 weeks. The drug was administered orally at a daily dosage 8.25 mg kg (-1). Mycologic status was assessed at the end of the treatment; and after follow-up at 2 days, and 4 and 9 weeks. The final evaluation revealed a complete mycologic cure of all cats by obtaining negative cultures, thereby demonstrating that terbinafine is an effective method of eradication of dermatophyte colonization.
引用
收藏
页码:95 / 97
页数:3
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